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How does handgrip strength training combined with inspiratory exercise influence blood pressure, heart rate, and cardiac effort in adults with normal blood pressure?

Evaluation of the effects of isometric resistance exercise and inspiratory muscle training on the hemodynamics of normotensive adult individuals

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4whfkqb
Enrollment
Unknown
Registered
2026-01-09
Start date
2024-11-10
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise

Interventions

This is a randomized, controlled, interventional clinical study with a crossover design composed of three experimental arms. The sample consisted of thirty-four male participants, with all thirty-four
however, both participants and the evaluator responsible for outcome measurements were unaware of the exercise load settings, characterizing partial blinding. After an initial physical and clinical as

Sponsors

Escola Bahiana de Medicina e Saúde Pública
Lead Sponsor
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
Collaborator

Eligibility

Sex/Gender
Male
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Healthy male volunteers; aged between 18 and 30 years; within ideal weight range; physically active or inactive.

Exclusion criteria

Exclusion criteria: History of cardiovascular or respiratory disease; smokers; high-risk classification for cardiovascular disease, with two or more risk factors, according to the guidelines for stress testing and its prescription from the American college of sports medicine; drug abuse; pre-existing musculoskeletal disorders or neurological, renal, hepatic, gastrointestinal, psychiatric, hematological or metabolic diseases

Design outcomes

Primary

MeasureTime frame
It is expected that the association of inspiratory muscle resistance with upper limb isometric exercise modifies the acute hemodynamic response when compared with isolated isometric exercise, with this outcome verified through the measurement of heart rate, systolic blood pressure, diastolic blood pressure, and rate pressure product at rest and throughout the sets of isometric handgrip exercise, with the outcome considered present when minimum increments equal to or greater than seven beats per minute in heart rate, ten millimeters of mercury in systolic blood pressure, and five millimeters of mercury in diastolic blood pressure are observed, as well as differences in absolute values and delta values of these variables between experimental protocols, calculated as the difference between exercise and rest, in addition to the behavior of these variables across the exercise sets. It is expected that the association of inspiratory muscle resistance with upper limb isometric exercise modifies perceived exertion when compared with isolated isometric exercise, with this outcome verified through the application of the Borg perceived exertion scale from six to twenty during the different moments of the experimental protocols, with the outcome considered present when differences in perceived exertion scores are observed between protocols and across the exercise sets.

Secondary

MeasureTime frame
No secondary outcomes are expected.

Countries

Brazil

Contacts

Public ContactRamon Barbosa

Escola Bahiana de Medicina e Saúde Pública

ramonmartinsbarbosa@hotmail.com+55-75-999086670

Outcome results

None listed

Source: REBEC (via WHO ICTRP)