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Effectiveness of Dentifrice with Fluoride Controlled-release System for Remineralization of White spot: Randomized clinical study

Effectiveness of Dentifrice with Fluoride Controlled-release System for Remineralization of White spot: Randomized clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4w8tdb
Enrollment
Unknown
Registered
2019-06-17
Start date
2017-08-07
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Caries

Interventions

Toothbrushing with experimental dentifrice. Experimental group 1: 20 volunteers used a dentifrice with 1100 ppm of fluoride incorporated in a controlled release system (100%)
Experimental group 2: 20 volunteers used a dentifrice with 1100 ppm of fluoride, 50% incorporated in a controlled release system and 50% in its free form
Control group: 21 volunteers used the dentifrice with 1100 ppm fluoride in its free form (conventional). Intraoral photographs were taken at three moments during the study (Baseline, 45 days and 90 da
Other
E06.761.726.794

Sponsors

Universidade Federal da Paraíba
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age of 10 to 16 years that accept to participate of the research (agreement of agreement) and with consent of the parents or responsible ones (TCLE); has at least one lesion of active white spot on the vestibular face.

Exclusion criteria

Exclusion criteria: orthodontic appliance users; have extensive caries lesions or tooth sensitivity; children who do not allow the clinical examination. Also excluded are children and adolescents who are not residents of the metropolitan area of João Pessoa or exposed to drinking water from wells or sources other than the city's supply network

Design outcomes

Primary

MeasureTime frame
Reduction of lesions of active white spot in the period of three months, determined through intraoral photographs, from the area reduction (mm2) in the measurements at the beginning, the middle and the end of the study

Secondary

MeasureTime frame
Reduction in the incidence of dental caries measured by clinical examination during the study period (three months)

Countries

Brazil

Contacts

Public ContactFábio Sampaio

Universidade Federal da Paraíba

fcsampa@gmail.com+55 083 3216 7795

Outcome results

None listed

Source: REBEC (via WHO ICTRP)