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Evaluation of photoprotection activity

Evaluation of a semi-solid formulation containing a combination of free and nanoencapsulated natural products for protection against solar radiation

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
REBEC
Registry ID
RBR-4w44wkd
Enrollment
Unknown
Registered
2024-12-13
Start date
2024-10-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neoplasms

Interventions

This is a controlled, one-arm, double-blind, pilot clinical study. Twenty healthy volunteers, men and women, aged 20 to 35 years, with no history of skin disease or skin cancer participated in the stu

Sponsors

Universidade Federal de Sergipe
Lead Sponsor
Universidade Federal de Sergipe
Collaborator

Eligibility

Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Healthy individuals;individuals aged 20-35 years;individuals with no history of dermatological disease;both sexes.

Exclusion criteria

Exclusion criteria: Individuals with skin lesions in the forearm area;individuals under 20 years of age or over 35 years of age;individuals with allergies to the components of the formulation

Design outcomes

Primary

MeasureTime frame
It is expected to obtain low levels of erythema, melanin and transepidermal water loss in the forearm areas of the 20 volunteers to whom the test formulation (dried hesperetin nanocapsules with titanium dioxide) and the commercial sunscreen were applied.

Secondary

MeasureTime frame
It is expected that no erythema will form in the area treated with the test formulation after 3 days of UVA-UVB irradiation.

Countries

Brazil

Contacts

Public ContactJose Adao Nascimento Júnior

Universidade Federal de Sergipe

adaocarvalho@academico.ufs.br+55(79)98497808

Outcome results

None listed

Source: REBEC (via WHO ICTRP)