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Effect of cardiopulmonary rehabilitation protocol on functionality, strength of breathing and body muscles and quality of life in COVID-19 patients

Effect of cardiopulmonary rehabilitation protocol on functionality, respiratory muscle e strength, perioheral and quality of life in patients recovered from COVID-19: a controlled and randomizes clinical study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
REBEC
Registry ID
RBR-4vzrfyf
Enrollment
Unknown
Registered
2022-01-26
Start date
2021-10-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronavirus infection of unspecified location

Interventions

After initial evaluation, patients in the Cardiopulmonary Rehabilitation Group, composed of 25 patients, will start a protocol lasting 6 weeks, 60 minutes a day, 2 days a week. Each session will inclu
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Sponsors

Hospital Otávio de Freitas
Lead Sponsor
Hospital Otávio de Freitas
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with at least six weeks after the clinical diagnosis of COVID-19, admitted and participating in the post COVID-19 cardiopulmonary rehabilitation protocol; Over 18 years of age; Both sexes; Presence of symptoms such as dyspnea, fatigue and functional impairment after recovery from COVID-19

Exclusion criteria

Exclusion criteria: Active stage of the disease; Inability to understand and execute commands; Osteoarticular and/or muscle deficit that does not allow walking or with limits to the implementation of the established protocol; Patient diagnosed with lung diseases such as Chronic Obstructive Pulmonary Disease (COPD), Asthma, Cystic Fibrosis, Post Tuberculosis Pulmonary Disease, among others; Patients who have absolute contraindications to perform the six-minute walk test (6MWT) which include the presence of unstable angina, uncontrolled systemic arterial hypertension, recent pulmonary embolism and heart attack that occurred in the month prior to the exam; Patients who drop out of treatment or have no 03 missing

Design outcomes

Primary

MeasureTime frame
1. It is expected to find improvement in functional capacity using the Walking Test from a 30-meter minute survey in measurements at least before and after the intervention.

Secondary

MeasureTime frame
2. To evaluate the increase in quadriceps muscle strength using the Medtech Dynamometer device, using the reference equation by Neder et al., 1999, comparing the predicted values in the pre- and post-intervention measurements. Considering the presence of muscle weakness, values are lower than 80% of the predicted value.;3. Assess the improvement in functional capacity, using the self-paced Six-Minute Step Test from a variation of at least 20 steps in pre- and post-intervention measurements.;4. To evaluate the improvement in inspiratory and expiratory muscle strength, using the Manovacuometry Test, using the reference equation by Costa et al., 2010, and to compare the predicted values in the pre- and post-intervention measurements. Whereas sarcopenia can be predicted by maximal inspiratory pressure less than 73cmH2O and maximal expiratory pressure less than 126cmH2O.;5. To evaluate the improvement in handgrip muscle strength using the Hangrip device", using the reference equation by Lopes et al., 2018, comparing the predicted values in the pre- and post-intervention measurements. Considering that the cutoff point for muscle weakness is values below 20 kgf for women and 30 kgf for men.;6. To assess the improvement in quality of life using the Quality of Life Assessment Instrument of the World Health Organization, considering a score greater than 60 as a cutoff point, to predict good and/or satisfied quality of life, in pre- and post-intervention measurements .;7. It is expected to find the race, the assessment of life with the positive assessment of the organization at a distance by test in the test of minutes found in the manovacuometry test, of the strength of quality whether the parametric data or not believe Spearman's parametric data.;8. It is expected to find a positive correlation between the number of steps climbed in the self-paced Six-Minute Step Test, with the values found in the manovacuometry test, handgrip strength assessment and the World Organization's

Countries

Brazil

Contacts

Public ContactMatheus Pinho
matheuspinhofisio@gmail.com+55 (81)99041505

Outcome results

None listed

Source: REBEC (via WHO ICTRP)