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Effect of maternal vitamin A supplementation on vitamins A and E in breast milk.

Assessment of maternal vitamin A supplementation on the retinol levels and alpha-tocopherol in human milk.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4v7j2d
Enrollment
Unknown
Registered
2015-05-18
Start date
2013-12-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamin E deficiency or vitamin A in the mother and newborn, maternal supplementation.

Interventions

Group 1 (control): 22 women with births at term, untreated, will not receive vitamin A supplementation after delivery, samples will be collected in 3 different days, distributed as follows: first coll
Dietary supplement

Sponsors

Universidade Federal do Rio Grande do Norte (Centro Cordenador)
Lead Sponsor
Universidade Federal do Rio Grande do Norte (Centro Cordenador)
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Healthy volunteers; term delivery; conception without defect; aged 18-45 years; without a history of miscarriage; without the use of vitamin supplements during pregnancy containing vitamin A or E.

Exclusion criteria

Exclusion criteria: Premature birth; diagnosis of gastrointestinal, infectious, liver, heart, syphilis, HIV positive or neoplasms; conceptus multiple; with use of vitamin supplements during pregnancy containing vitamin A or E.

Design outcomes

Primary

MeasureTime frame
Increase in retinol concentration and reduction of alpha-tocopherol concentration in breast milk in 30 days, after supplementation, verified by the Student t test from the variation of finding these vitamin concentrations in colostrum and mature milk.

Secondary

MeasureTime frame
Increasing concentrations of retinol and a reduction of alpha-tocopherol concentration in colostrum milk within 24 hours after supplementation verified by the Student t test variation from finding these vitamin concentrations in colostrum milk, before and after supplementation.

Countries

Brazil

Contacts

Public ContactEvellyn;Roberto Grilo;Dimenstein

Universidade Federal do Rio Grande do Norte;Universidade Federal do Rio Grande do Norte

evellyn-cg@hotmail.com;rdimenstein@gmail.com+55(84)3201-2394;558432153416

Outcome results

None listed

Source: REBEC (via WHO ICTRP)