primary open-angle glaucoma
Conditions
Interventions
Patients with primary open angle glaucoma (POAG), ocular hypertension (OH), pseudoexfoliative glaucoma, pigmentary glaucoma or patients with pigment dispersion syndrome, with inadequate control of int
Group 2. 40 patients will be instructed to use 1% prednisolone acetate eye drops 4 times a day for 7 days after SLT
Group 3. 40 patients will be instructed to use 0.1% prednisolone acetate eye drops 4 times a day for 7 days after SLT
Group 4. 40 patients will be instructed to use 0.1% nepafenac eye drops 4 times a day for 7 days after SLT. Data on IOP, number of eye drops and complications will be obtained at intervals: 7 days, 30
Sponsors
Hospital Oftalmológico de Brasília
Hospital Oftalmológico de Brasília
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with primary open-angle glaucoma or ocular hypertension or pseudoexfoliative glaucoma or pigmentary glaucoma or pigment dispersion syndrome, with inadequate control of intraocular pressure or intolerance to topical treatment, that will undergo selective laser trabeculoplasty (SLT). Patients approached must be at least 18 years of age on the date of the procedure and be able to undergo post-SLT follow-up for at least 12 months
Exclusion criteria
Exclusion criteria: Angle-closure glaucoma; Any previous glaucoma surgery; Any previous corneal procedure (refractive surgery, intrastromal rings, corneal transplant); Pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the success of selective laser trabeculoplasty (SLT) at the end of follow-up. The definition of success will be a 20% reduction in pre laser baseline intraocular pressure (IOP) and IOP less than 21mmHg. Failure criteria will be: failure to reach previously defined IOP values and need for retreatment, or need for glaucoma surgery during follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes will include changes in visual field and visual acuity (VA) and post selective laser trabeculoplasty (SLT) mean deviation (MD). In addition, we will assess predictors of success and complication rate. The pressure reduction obtained with the use of pilocarpine eye drops prior to SLT will be used as a predictor of SLT success | — |
Countries
Brazil
Contacts
Public ContactLaura Oltramari
Hospital Oftalmológico de Brasília
Outcome results
None listed