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Evaluation of resin with antimicrobial

In situ evaluation of the microbiological behavior of acrylic resins with an incorporation of chlorhexidine

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4tk434
Enrollment
Unknown
Registered
2018-07-13
Start date
2016-11-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biofilm

Interventions

A total of 34 healthy systemic individuals of both sexes over 18 years and under 35 years old will be selected, who will be submitted to rigorous anamnesis to include: (1) a healthy individual with no
(2) do not use removable dentures
(3) is not under orthodontic treatment
(4) absence of cleft palate that prevents the use of plaque
(5) absence of active caries or periodontal disease with depth at probing greater than 4 mm
(6) patients who are not in use, or who have received prior treatment (3 months) with antibiotics
(7) is not using antimicrobial oral antiseptic before and during the study. In an initial consultation for the selection of volunteers, patients will undergo a complete clinical and periodontal examin
another disk with 0.5% CLX discs
and a third plate with 1% CLX discs. Each intraoral device will be used for 24 hours. The rest time between one plate and another will be 72 hours. The order of use of each individual's plaques will b
Other
D02.078.370.141.100
D02.241.081.069.800.550.500

Sponsors

Universidade do Estado do Rio de Janeiro
Lead Sponsor
Departamento de Prótese da Faculdade de Odontologia da Universidade do Estado do Rio de Janeiro
Collaborator

Eligibility

Age
18 Years to 32 Years

Inclusion criteria

Inclusion criteria: Male or female, aged between 18 to 32, healthy with no history or presence of a systemic disease, and absence of active caries or periodontal disease.

Exclusion criteria

Exclusion criteria: Individuals with removable prosthesis, orthodontic appliances or any dental implants; pregnant or breastfeeding; smokers; presence of cleft palate that precludes the wearing of a retainer; use of an antimicrobial mouthwash prior to enrolment in the study; and use of antibiotics against infectious diseases during the 3 months prior to the study.

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: The reduction of biofilm formation on the surface of the acrylic resin in chlorhexidine is expected to be 50% compared to the control group after 24 hours in the buccal medium. The method used was by counting colonies on blood agar medium and Streptococcus mutans.;Conclusion1: There was no decrease in biofilm formation on the acrylic resin surface with chlorhexidine compared to the control group after 24 hours in the buccal medium. The method used was by counting colonies on blood agar medium and Streptococcus mutans.

Secondary

MeasureTime frame
Secondary outcomes are not expected

Countries

Brazil

Contacts

Public ContactCaroline Maluf

Departamento de Prótese da Faculdade de Odontologia da UERJ

carolinemaluf@hotmail.com55 21 967845679

Outcome results

None listed

Source: REBEC (via WHO ICTRP)