Pathological conditions, signs and symptoms
Conditions
Interventions
Control group: 79 children with central venous catheter who received the administration of 2 ml saline intravenously 4x / day in each route with intermittent infusion and 2x / day in each route with c
from the day of insertion of the central venous catheter to the day of removal.
Study group: 73 children with central venous catheter who received 2 ml ascorbic acid 25 mg / ml intravenously 4x / day
from the day of insertion of the central venous catheter to the day of removal.
Drug
Sponsors
Complexo do Hospital de Clínicas da Universidade Federal do Paraná
Complexo do Hospital de Clínicas da Universidade Federal do Paraná
Eligibility
Age
28 Days to 14 Years
Inclusion criteria
Inclusion criteria: Children between 28 days and 13 years 11 months and 29 days will be included in the study, using a single or double lumen central venous catheter, with the consent of the parents and/or guardians by signing the Free and Informed Consent Term - TCLE added to the Free and Informed Consent Term and that are not accompanied by serum bilirubin dosage
Exclusion criteria
Exclusion criteria: Will be excluded from the study: Carriers of nephrological diseases, clotting disorders and/or hemochromatosis; research subjects with parents under 18 years of age; research subjects whose guardians do not consent to or withdraw from the CLT; research subjects whose do not consent to or withdraw from the CLT; children with bilirubin dosage; newborns under 28 days of age; fully implanted catheter carriers; entry of medicines incompatible with ascorbic acid (etomidate, propofol, tipental, amikacin, vancomycin)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the expected primary outcome of the research was the total obstruction of the lumen of the central venous catheter, monitored daily by the researcher and diagnosed by the nursing staff of the services involved.;the primary outcome occurred in 11.185% of the central venous catheters. | — |
Secondary
| Measure | Time frame |
|---|---|
| The expected secondary outcome was the removal of the central venous catheter, electively or motivated by complications in 100% of the research subjects.;The researcher followed up daily, from the day of insertion of the central venous catheter to the day of its removal, and 100% of the 152 subjects who composed the sample had their catheter removed. | — |
Countries
Brazil
Contacts
Public ContactLeticia Giacomozzi
Complexo do Hospital de Clínicas da Universidade Federal do Paraná
Outcome results
None listed