Pregnant with type 1 diabetes mellitus
Conditions
Interventions
The study will be defined two study groups:
Group 1 (G1) - control group of 20 pregnant women who receive guidance from the traditional diet routinely adopted in the studied maternity. Pregnant women
Other
G07.203.650.240
Sponsors
Universidade Federal do Rio de Janeiro - UFRJ
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Eligibility
Sex/Gender
Female
Age
18 Years to 49 Years
Inclusion criteria
Inclusion criteria: Pregnant adults, diagnosis of diabetes mellitus ( types 1 and 2 ) of singleton pregnancy; non-smokers and non-users of alcohol; gestational age up to 28 weeks.
Exclusion criteria
Exclusion criteria: Pregnant women with chronic comorbidities such as kidney or liver disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hypertensive disorders of pregnancy;For the diagnosis of syndromes Hypertensive Pregnancy, will be investigated - gestational hypertension when blood pressure is greater than or equal to 140/90 mmHg without proteinuria, which occurs after the 20th week of gestation; preeclampsia - Gradual development of hypertension and proteinuria -excreção of 0.3 g or more protein in urine 24 hours; eclampsia - presence of seizures in women with hypertensive frame, not caused by epilepsy or other seizure disorder | — |
Secondary
| Measure | Time frame |
|---|---|
| Inadequacy of gestational weight gain entirely when above or below recommended for pre-pregnancy body mass index. It will be assessed the total weight gain during pregnancy, calculated as the difference between the pre-birth weight and pre-pregnancy weight. Inadequate dietary intake of energy, macronutrients and micronutrients - will be compared to the consumption before the intervention and after the intervention and each trimester of pregnancy and compared with the intake recommendations for pregnant women. Consumption will be ranked below the recommended level or above recommendation. Gestational anemia will be determined by the concentration of hemoglobin and when it is less than 11g / dL is considered anemia. Lack of vitamin A will be assessed by the indicator gestational night blindness, diagnosed with the implementation of standardized interview during pregnancy. The other co-morbidities during pregnancy, childbirth or the postpartum period, such as urinary tract infection, premature rupture of membranes, oligohydramnios or polyhydramnios will be identified in medical records in order. The loss of glycemic control will be investigated in all quarters, according to maternal fasting glucose and postprandial glucose (1 hour). The loss of glycemic control will be identified when the fasting blood glucose is greater than or equal to 95mg / dL and postprandial 2 hours after the start of the meal is greater than or equal to 140mg / dL. The lipid profile and oxidative stress markers will be evaluated every 8 weeks after the start of the intervention (baseline). To evaluate the lipid profile will be analyzed total cholesterol parameters, HDL cholesterol and triglycerides, LDL cholesterol and VLDL. The assessed oxidative stress markers will be - Total glutathione, total antioxidant capacity (TAC), plasma nitrite, MDA-TBARS (malondialdehyde). The macrosomia will be identified by the higher birth weight or equal to 4000g. Premature birth is considered when deliver | — |
Countries
Brazil
Contacts
Public ContactClaudia Saunders
Universidade Federal do Rio de Janeiro - UFRJ
Outcome results
None listed