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Red light therapy to control bacteria adhered to orthodontic devices

Photodynamic therapy to control biofilm adhered to orthodontic brackets

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4t7wq67
Enrollment
Unknown
Registered
2024-01-20
Start date
2023-08-23
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Photochemotherapy

Interventions

This is a randomized controlled, double-blind clinical study. Experimental group: 24 volunteers, volunteers must have the 4 upper premolars intact, totaling 96 dental elements. Each volunteer will rec
Intervention 02 - Application of antimicrobial photodynamic therapy with a low-power red laser with energy of 3 J at 3 application points: Incisal, mesiocervical and central
Intervention 03 - Application of 0.12% chlorhexidine for 1 minute around the bracket (positive control)
Intervention 04 - Application of sterile 0.9% saline solution for 1 minute around the bracket. Microorganisms will be collected at three stages, before applying the interventions, immediately after ap
E02.594.540

Sponsors

Fundação Hermínio Ometto
Lead Sponsor
Faculdade de integração do sertão - FIS
Collaborator

Eligibility

Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Volunteers must present the 4 upper premolars intact, without restoration or abnormalities involving the buccal surface.

Exclusion criteria

Exclusion criteria: Those who are using antibiotics, who do not follow oral hygiene instructions, who are hypersensitive to dyes, pregnant women, smokers, who are undergoing previous orthodontic treatment, who have periodontal disease, calculus, cavities in selected teeth, the presence of orthodontic appliances and /or fixed retention and the presence of occlusal changes such as: crowding, rotation, extrusion or intrusion of the selected teeth will be excluded from the sample.

Design outcomes

Primary

MeasureTime frame
It is expected to define the best intervention to reduce microorganisms adhered around orthodontic brackets

Secondary

MeasureTime frame
It is expected to define the best protocol for carrying out photodynamic therapy to reduce microorganisms around orthodontic brackets.

Countries

Brazil

Contacts

Public ContactVinícius Magalhães

Fundação Hermínio Ometto

viniciussoutoodonto@gmail.com+55(081) 9 99317290

Outcome results

None listed

Source: REBEC (via WHO ICTRP)