Pathological conditions, signs and symptoms
Conditions
Interventions
Experimental group: 40 patients with oral and oropharyngeal cancer submitted to radiotherapy, with ended therapy for more than 3 months, will use a gel with humectant properties, 5 times a day, passin
Drug
Procedure/surgery
Radiation
Other
L01.178.682.192.836.535.310
E01.370.350.600.631
Q10.020
V03.175.250
E01.370.350.700.225
Sponsors
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo - HCFMRP/USP
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo - HCFMRP/USP
Eligibility
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Men; Women; over 18 years old; history of oral cavity neoplasm treated with radiotherapy for more than 3 months and less than 2 years after termination
Exclusion criteria
Exclusion criteria: Sjogren's Syndrome; Graft versus Host Disease (GVHD); Hepatitis B and C; HIV; Sarcoidosis; other diseases of the connecting tissues; physical or mental illness at the time of the examination;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Is expected to improve the perception of xerostomia reported by the patient before the start of the study ;Is expected reduction of the incidence of candidosis in the gel group with the hydration formula;Positive repercussions are expected regarding the function of swallowing and the possible improvement in taste and smell;The Wilcoxon non-parametric tests with paired Bonferroni and Mann-Whitney correction will be used to analyze the differences found between groups A and B at all times by analyzing the domains related to quality of life UWQOLQ and perception of xerostomia XI. exact Chi-square (X2) will be used for comparison between groups in the socio-demographic domains. Friedman's non-parametric test will be used to compare the values ??obtained in the non-stimulated salivary flow and pH. All analyzes adopted a level of significance greater than p greater than 0.05 | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected | — |
Countries
Brazil
Contacts
Public ContactComitê de ;Gabriela Pesquisa;de Araujo
Universidade de São Paulo - Ribeirão Preto;Universidade de São Paulo - Ribeirão Preto
Outcome results
None listed