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Clinical evaluation of tooth whitening with violet light

Long-term clinical evaluation in-office dental bleaching using violet LED light (405-410 nm)

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4s4jv7v
Enrollment
Unknown
Registered
2025-10-31
Start date
2025-09-22
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth discoloration

Interventions

This is a four-arm, double-blind, randomized controlled clinical trial. The objective of this clinical study will be to evaluate different dental whitening protocols associated with violet LED light (
G2 - hybrid technique using violet LED light (15 min, 10 min on, and 5 min without light) + 35% hydrogen peroxide-based whitening gel (1 x 15 min + light, 4 sessions, 1 session/week) - total of 30 min
G3 - 35% hydrogen peroxide-based whitening gel (1 x 15 min, 4 sessions, 1 session/week)
G4 - hybrid technique using violet LED light (10 min, 7 min on, and 3.5 min off) + 35% hydrogen peroxide-based whitening gel (1x 10 min + light, 4 sessions, 1 session/week) – total of 20 min of whiten

Sponsors

Faculdade de Odontologia da Universidade de São Paulo (Fousp)
Lead Sponsor
Faculdade de Odontologia da Universidade de São Paulo (Fousp)
Collaborator

Eligibility

Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Minimum age of 18 years and maximum age of 30 years; presence of all dental elements, without aesthetic restorations or caries lesions in the upper and lower anterior teeth; and participants with canine tooth color of A3 or darker, according to the VITA® Classical Color Scale

Exclusion criteria

Exclusion criteria: Presence of any type of systemic pathology; presence of periodontal disease; systematic use of tobacco and alcoholic beverages; participants with teeth discolored by tetracycline, fluorosis, endodontic treatment; participants with a history of self-reported tooth sensitivity; pregnant or breastfeeding female participants; presence of crowns or restorations on the anterior teeth (15 to 25 and 35 to 45); and participants with bruxism or undergoing treatment with medication with anti-inflammatory, analgesic and/or antioxidant action

Design outcomes

Primary

MeasureTime frame
It is expected to observe the color change of the tooth.

Secondary

MeasureTime frame
It is expected to observe dental sensitivity and changes in enamel surface morphology.

Countries

Brazil

Contacts

Public ContactPatricia Freitas

Faculdade de Odontologia da Universidade de São Paulo (Fousp)

pfreitas@usp.br+55 11 3091-8455

Outcome results

None listed

Source: REBEC (via WHO ICTRP)