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Performance evaluation of peri-implant Mucositis treatment using Subgingival Polishing with Erythritol Powder

Treatment of peri-implant Mucositis with Subgingival Polishing

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4rzc3gk
Enrollment
Unknown
Registered
2025-06-27
Start date
2025-06-02
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Implants

Interventions

This is a randomized controlled clinical trial of split-mouth nature, with 2 evaluation groups. Control Group: 20 adult patients of both sexes, with a minimum age of 18 and a maximum of 80 years old,
D02.078.370.141.100

Sponsors

Associação Unificada Paulista de Ensino Renovado Objetivo
Lead Sponsor
Faculdade de Odontologia da Universidade Paulista (UNIP)
Collaborator

Eligibility

Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patient aged between 18 and 80 years; both sexes; who have had dental implants in place for at least 12 months; diagnosis of peri-implant mucositis is made based on the presence of signs of peri-implant inflammation (redness, edema and bleeding 30 seconds after probing); absence of additional bone loss after initial healing (higher than 2mm)

Exclusion criteria

Exclusion criteria: Pregnant and lactating women; individuals with systemic diseases (osteoporosis, immunological disorders, hepatitis, diabetes mellitus); patients with active periodontitis and peri-implantitis; use of corticosteroids, non-steroidal anti-inflammatory drugs, immunosuppressive drugs, antibiotics, estrogen and estrogen receptor modulators, alentronate and calcitonin during the 6 months prior to the study

Design outcomes

Primary

MeasureTime frame
It is expected that it will be possible to evaluate the effect of using subgingival blasting with erythritol powder on peri-implant mucositis, through the analysis of peri-implant health—

Secondary

MeasureTime frame
It is expected that it will be possible to evaluate the effect of the use of subgingival blasting with erythritol powder on peri-implant mucositis, through the analysis of peri-implant health, through evaluations of the local profile of anti- and pro-inflammatory mediators and factors related to bone metabolism - IL-1ß, IL-4, IL-6, IL-10, IL-17, TGF-ß, TNF-a, INF-?, DKK1, OC, OPN, OPG, SOST, RANKL, MMP-1, MMP-2, MMP-9 - present in the peri-implant fluid; of the peri-implant microbiome; and of the patient-centered evaluation—

Countries

Brazil

Contacts

Public ContactRaissa Machado

Universidade Paulista

raissa.machado3@docente.unip.br+55 (11) 55864093

Outcome results

None listed

Source: REBEC (via WHO ICTRP)