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Evaluation of the use of alkalized Lidocaine in tracheal tube inflation in patients undergoing thyroid removal surgery

Evaluation of the use of alkalized Lidocaine in endotracheal tube cuff inflation in patients undergoing thyroidectomy surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4rvdvfk
Enrollment
Unknown
Registered
2022-12-19
Start date
2020-08-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intratracheal Intubation

Interventions

Patients between 18 and 70 years of age who underwent total or partial thyroidectomy surgery, of both sexes, ASA I or ASA II, and who agreed to sign the Free and Informed Consent Form (ICF) were inclu
patients with difficult orotracheal intubation (OTI) (trachea not intubated on the first attempt)
smoking patients
cuff rupture during OTI
patients with heart, lung, or neuropathies
patients with previous surgery of the larynx or trachea, with risk of aspiration of gastric contents, and with the need to use a nasogastric tube. With an average of 12 procedures per month, a 95% co

Sponsors

Hospital São Domingos
Lead Sponsor
Hospital São Domingos
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients over 18 years of age; men or women; who had undergone total or partial thyroidectomy; Classification of ASA grade I or II; who agreed to sign the free and informed consent

Exclusion criteria

Exclusion criteria: Patients who refused to participate in the study; patients with difficult orotracheal intubation (OTI) (trachea not intubated on the first attempt); smoking patients; cuff rupture during OTI; patients with cardiac, pulmonary, or neuropathies; patients with previous laryngeal and/or tracheal surgeries, with risk of aspiration of gastric contents, and with the need to use a nasogastric tube were excluded

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: It is expected to observe a lower physiological reflex during extubation, shorter time to wake up and recover from speech, as well as lower perioperative pressure levels in the lidocaine group.;Found outcome 1: There was no protective effect of the use of physiological reflex damage during extubation, time to wake up and speech recovery, on perioperative pressure levels in the lidocaine group.

Secondary

MeasureTime frame
Expected outcome 2: Observe protective effect on swallowing sensation, Ability to sustain phonation and sustain adequate volume and complaints, dysphonia, emesis, vocal fatigue, hemoptysis, airway inflammation, fullness, hoarseness, foreign body sensation, whisper, cough, fullness , hoarseness and foreign body sensation in the lidocaine group.;Found outcome 2: There was no protective effect on the sensation of swallowing, Ability to sustain phonation and sustain adequate volume and complaints, dysphonia, emesis, vocal fatigue, hemoptysis, airway inflammation, fullness, hoarseness, foreign body sensation, whisper, cough , fullness, hoarseness and foreign body sensation in the lidocaine group.

Countries

Brazil

Contacts

Public ContactPlinio Leal

Hospital São Domingos

pliniocunhaleal@hotmail.com+55 (98) 3216-8113

Outcome results

None listed

Source: REBEC (via WHO ICTRP)