Polycystic Ovary Syndrome
Conditions
Interventions
Control group: 15 women with polycystic ovary syndrome will receive standard advice for regular physical activity. The control group will be instructed to accumulate 30 minutes of moderate aerobic act
Behavioural
G11.427.590.530.698.277
Sponsors
Universidade Federal do Rio Grande do Norte - UFRN
Hospital Universitário Onofre Lopes – HUOL-UFRN
Eligibility
Sex/Gender
Female
Age
18 Years to 34 Years
Inclusion criteria
Inclusion criteria: Diagnosis of polycystic ovary syndrome according to the Rotterdam criteria
Exclusion criteria
Exclusion criteria: Other disorders such as nonclassic congenital adrenal hyperplasia, thyroid dysfunction, and hyperprolactinemia; renal or hepatic dysfunction; or use of medications known to affect reproductive, cardiovascular or metabolic function
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increased maximal oxygen uptake after 16 weeks of physical training, verified by ergospirometry, from of a change of at least 10% in the pre- and post-intervention measurements | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of the reproductive, hormonal and metabolic aspects after 16 weeks of physical training, verified by ovarian morphological analysis and levels of luteinizing hormone, follicle-stimulating hormone, progesterone, 17-hydroxyprogesterone, total testosterone, dehydroepiandrosterone sulfate, prolactin, sex hormone-binding globulin, total cholesterol, high density lipoprotein, triglycerides, urea, creatinine, C-reactive protein, plasminogen activator inhibitor-1, glucose and insulin, from the observation of a significant change in the pre- and post-intervention measurements;Improvement of the cardiovascular aspect after 16 weeks of physical training, verified by blood pressure and heart rate, from the observation of a significant change in the pre- and post-intervention measurements;Improvement of body composition after 16 weeks of physical training, verified by body mass, body mass index, and waist and hip circumference, from the observation of a significant change in the pre- and post-intervention measurements;Improvement in quality of life after 16 weeks of physical training, verified by quality of life questionnaire, from the observation of a significant change in the pre- and post-intervention measurements | — |
Countries
Brazil
Contacts
Public ContactEduardo;George Costa;de Azevedo
Universidade Federal do Rio Grande do Norte - UFRN;Universidade Federal do Rio Grande do Norte - UFRN
Outcome results
None listed