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Theory of chaos applied to spinal anesthesia

Fractal and chaotic behavior of heart rate variability in subarachnoid anesthesia - hrv: heart rate variabity

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4q53d6
Enrollment
Unknown
Registered
2018-08-10
Start date
2018-06-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal anesthesia hypotension Autonomic nervous system

Interventions

Crossover study. Experimental group: 60 patients ASA I to III, to undergo orthopedic surgery of lower limbs under spinal anesthesia. The HRV will be evaluated after 20 min of the anesthetic block inst
Procedure/surgery
Other
E03.160
E04.525.210.105

Sponsors

Hospital Universitário Júluio Bandeira
Lead Sponsor
Hospital Universitário Júluio Bandeira
Collaborator

Eligibility

Age
14 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with physical status ASA I, II or III submitted to orthopedic surgical procedure of lower limbs under spinal anesthesia. By orientation and signature of the TCLE. Aged between 14 and 99 years. Sample : 60 patients.

Exclusion criteria

Exclusion criteria: Patients who use beta blockers or other drugs and conditions that alter the autonomic balance. Patients who refused to sign the EHIC. Patients with bleeding loss expected above 500 ml. General anesthesia, peripheral nerve blocks, epidural.

Design outcomes

Primary

MeasureTime frame
Expected outcome: higher incidence of arterial hypotension after spinal anesthesia in patients with low heart rate variability. Decreased HRV values after spinal anesthesia and low values at discharge.;Observed outcome: patients with low heart rate variability, measured by DFA and approximate entropy analysis, had a 20% higher incidence of perioperative hypotension. reduction in HRV values during the installation of spinal anesthesia and incomplete recovery at discharge, reflecting persistence of autonomic block even after recovery from motor function.

Secondary

MeasureTime frame
Expected outcome: hypotension in patients with low HRV at rest.;Observed outcome: 20% higher incidence of hypotension in patients with low HRV measured by DFA and approximate entropy.

Countries

Brazil

Contacts

Public ContactHermes;Luiz Batista;Abreu

Hermes Melo Teixeira Batista;Faculdade de Medicina do ABC

hermesmelo@oi.com.br;rbcdh.fsp@gmail.com+55(88)99280669;88999280669

Outcome results

None listed

Source: REBEC (via WHO ICTRP)