Cigarette smoking, impairment of mucociliary clearance
Conditions
Interventions
After initial assessment for obtaining personal data, smoking history, lung function, respiratory affections research, exhaustive and progressive treadmill test for the individual prescribing exercise
2)moderate aerobic exercise for 20 minutes
3)smoking two cigarettes for 20 minutes, and 4)rest for 20 minutes in a sitting position. At the end of each intervention will be evaluated: heart rate variability, exhaled carbon monoxide, mucociliar
Other
G11.427.590.530.698.277
Sponsors
Universidade Estadual Paulista "Júlio de Mesquita Filho" - Faculdade de Ciências e Tecnologia
Departamento de Fisioterapia da Universidade Estadual Paulista "Júlio de Mesquita Filho" - Faculdade de Ciências e Tecnologia
Eligibility
Age
30 Years to 50 Years
Inclusion criteria
Inclusion criteria: Subjects between 30 and 50 years old, both genders, with normal lung function attested by spirometry and absence of illnesses that interfere with exercise performance or autonomic modulation (eg, cerebrovascular, cardiac, orthopedic, rheumatic or metabolic disease, diabetes, alcoholism).
Exclusion criteria
Exclusion criteria: Not comprehension or non-cooperation on the procedures and methods of research; non-attendance at one of the days of the experimental protocol; subjects with lung disease diagnosed, history of surgery or nasal trauma, nasal septal deviation or inflammation of the upper airways observed in clinical evaluation during the interview and experimental protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increased mucociliary clearance activity of smokers and nonsmokers after the exercise stimulus, evaluated by the saccharin transit time test. | — |
Secondary
| Measure | Time frame |
|---|---|
| There was an increase in mucociliary clearance activity after the exercise stimulus in smokers and nonsmokers. However, it was not expected that this response was similar between both groups, as observed in this study. For interventions, exercise followed by smoking and isolated smoking there was also an increase in mucociliary clearance in smokers, but without statistical differences among these (exercise followed by smoking, isolated exercise and isolated smoking) interventions. At rest, there was no significant alteration in mucociliary clearance in smokers and nonsmokers. | — |
Countries
Brazil
Contacts
Public ContactErcy Cipulo Ramos
UNESP
Outcome results
None listed