Vulvar Sclerosus Lichen
Conditions
Interventions
The first 15 patients selected at the outpatient clinic will be treated with Clobetasol daily in the first month of disease, followed by alternate day applications in the second month, and an applicat
Radiation
E02.594
Sponsors
Hospital Universitário da Universidade Federal de Juiz de Fora - UFJF
Hospital Universitário da Universidade Federal de Juiz de Fora - UFJF
Eligibility
Sex/Gender
Female
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Women attended at the outpatient clinic of the Gynecology Service of the University Hospital of the Federal University of Juiz de Fora - UFJF, with genital atrophic lichen sclerosus diagnosed by histopathological evaluation of vulvar biopsy.
Exclusion criteria
Exclusion criteria: Women who have used or used other therapeutic methods for lichen in the last 30 days; women with differential diagnoses identified in the biopsy, such as vulvar intraepithelial neoplasia or vitiligo.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the results of the treatment of lichen sclerosus with Clobetasol and the treatment with laser therapy with regard to the perception of improvement of patients' quality of life and the vulvar anatomical manifestations of the disease. In the first case, the analysis will be performed by comparing the scores obtained in each domain in the application of the questionnaire. In the second case, the analysis will be performed by comparing the presence of clinical signs of the disease and the extent of vulvar involvement, being classified as absent, mild (less than 30% of the vulva), moderate (30 to 50% of the vulva) or severe (more than 50% of the vulva). | — |
Secondary
| Measure | Time frame |
|---|---|
| To analyze the profile of women affected by lichen sclerosus regarding epidemiological aspects: current age, age of diagnosis, color, marital status, schooling, associated comorbidities, among others. ;To evaluate the degree of impairment of the quality of life of the patients studied through the evaluation of the score obtained in the questionnaire response. ;To describe the lesions and their evolution from the treatments used based on the observation of the genitalia during the physical examination and the evaluation of the photographs, comparing possible remissions of clinical signs, skin color and texture, for example. | — |
Countries
Brazil
Contacts
Public ContactHakayna Salgado
Hospital Universitário da Universidade Federal de Juiz de Fora - UFJF
Outcome results
None listed