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Physical exercise with limitation of blood flow to the forearm in renal patients: randomized clinical trial

Efficacy of physical exercise with restriction of blood flow on the blood vessels of the forearm pre and post-confection of arteriovenous fistula in Chronic Kidney Disease: randomized clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4p6fk2
Enrollment
Unknown
Registered
2018-08-09
Start date
2018-07-31
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Renal Insufficiency

Interventions

3 groups will be formed: 1- Group with restriction of blood flow (10 patients) 2- Group without restriction of blood flow (10 patients) 3- Group that will do the conventional training (10 patient
finger flexion with adjustable load handgrip
and isometric flexion of fingers using a tennis ball. The third group will perform the conventional training of finger flexion with tennis ball and the training will last 8 weeks. After 8 weeks the
Other
G11.427.410.698.277
E02.779.474

Sponsors

Universidade Federal da Pernambuco
Lead Sponsor
Universidade Federal da Pernambuco
Collaborator

Eligibility

Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: The study will include patients with stage 4 or 5 chronic kidney disease; of both sexes, aged between 18 and 60 years; in conservativ treatment or dialysis; and who have medical indication for the manufacture of arteriovenous fistula for the performance of hemodialysis.

Exclusion criteria

Exclusion criteria: Those that present cognitive deficits that may interfere in the understanding of the evaluation process or the accomplishment of the activities will be excluded; patients with a history of arteriovenous fistula production in the upper limbs or who have undergone previous local vascular procedure; those that perform manual activity with high loads; and that presented traumatic-orthopedic injuries in cervical, shoulder, elbow, wrist and hand; and those with signs of thrombophlebitis and hypoplasia / agenesis of the upper limbs.

Design outcomes

Primary

MeasureTime frame
Increased basal diameter (in millimeters) of the cephalic vein of at least 0.2 millimeters, in the forearm of the upper limb to be made the arteriovenous fistula after training with restriction of blood flow for the group with restriction. It will be checked by ultrasonography of the vessels of the forearm.

Secondary

MeasureTime frame
Increased distensibility of the cephalic vein (in millimeters) after the application of blood flow restriction. ;Increase in the diameter (in millimeters) of the radial artery. Verified by ultrasonography of the vessels of the forearm;Flow velocity - systolic peak (cm / s) of the radial artery. Verified by ultrasonography of the vessels of the forearm;Mean velocity (cm / s) of the radial artery. Verified by ultrasonography of the vessels of the forearm.;Increase of forearm circumference (in centimeters), checked with tape measure.;Manual grip strength (Kgf),verified with dynamometer.

Countries

Brazil

Contacts

Public ContactShirley Bezerra

Universidade Federal da Pernambuco

shi.dias.b@gmail.com+55081996693769

Outcome results

None listed

Source: REBEC (via WHO ICTRP)