Obesity
Conditions
Interventions
Thirty-six adults with obesity of both sexes were recruited, among employees, students, companions of patients and other people that circulate through the Hospital das Clínicas of FMRP-USP
Campus of USP of Ribeirão Preto - SP
and surroundings. A randomized controlled clinical trial was used to compare two study diets over a 6-week period. Participants were instructed not to eat any type of nuts (including peanuts and baru
3. limit the consumption of processed foods
4. Avoiding the consumption of ultraprocessed foods) that are part of the 10 steps for an adequate and healthy diet of the Food Guide for the Brazilian Population - 2nd Edition (2014)
was instructed not to consume any type of nuts (including peanuts and baru nuts) in the diet
and to maintain the same level of habitual physical activity during the 6 weeks of intervention. The nut group received the same orientations as the control group, but with the inclusion of 30 grams o
Dietary supplement
G07.203.300.456
Sponsors
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Eligibility
Age
20 Years to 59 Years
Inclusion criteria
Inclusion criteria: Volunteers aged 20 to 59 years; body mass index (BMI) equal to or greater than 30 kg / m² due to excess body fat; who agreed to participate voluntarily in the study; and that they would be willing to follow the proposed recommendations.
Exclusion criteria
Exclusion criteria: Participants with: 1) psychiatric disorders, history of cancer, endocrine disorders (adrenal diseases, thyroid diseases, polycystic ovarian syndrome, diabetes mellitus and dyslipidemia in drug and non-drug treatment), spoliation status (fever, malabsorption syndrome, surgery), inflammatory, infectious, autoimmune, renal, cardiovascular, hepatic (cirrhosis, hepatitis, and hepatic insufficiency) diseases; 2) use of weight-loss, appetite-suppressing, immunosuppressive, anti-inflammatory, corticosteroid, antibiotic, hypolipidemic, antidiabetic, anticoagulant, antihypertensive, hormonal (except stable contraceptive use for at least 6 months); 3) frequent consumption of nuts, including peanuts and baru almonds (one or more times in the week); 4) allergy or food intolerance to any type of nuts (including peanuts or baru almonds); 5) use of dietary supplements; 6) alcoholics, smokers or drug abuse; 7) women in climacteric, pregnant and nursing mothers; 8) performing restrictive diet or dietary treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find an average difference in total cholesterol of at least 0.8 mmol/L between the nut group and the control group after the intervention, measured from blood sample by enzymatic method. Therefore, a greater reduction in total cholesterol in the nut group compared to the control group is expected. | — |
Secondary
| Measure | Time frame |
|---|---|
| A statistically significant reduction associated with a p-value less than 0.05 is expected to be found in LDL (low density lipoprotein), triglyceride, glycemia, insulin, inflammation markers and oxidative stress levels in the nut group when compared to the control group after intervention, measured from blood sample (plasma or serum) by laboratory tests. | — |
Countries
Brazil
Contacts
Public ContactAnderson Navarro
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Outcome results
None listed