Hepatitis C virus-infected patients, insulin resistance
Conditions
Interventions
Patients (n-100) will receive basic nutritional orientations based on healthy eating and will be divided into two groups according to the type of supplementation with either omega-3 (1080mg of EPA pl
dietary supplement
Sponsors
Universidade Federal da Bahia
Universidade Federal da Bahia
Eligibility
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Adults (age > 18 years) diagnosed with chronic hepatitis C (genotype I); either non responders or naive patients; alcohol consumption 2.5; Signature of term consent
Exclusion criteria
Exclusion criteria: Diabetics or those using drugs to alleviate insulin resistance, co-infected (HIV or HBV), hepatitis with autoimmune or use of antiviral treatment (interferon and ribavirin), decompensated liver disease or patients with hepatocellular carcinoma; With other neoplasias; Patients with chronic renal failure or decompensated heart failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of insulin resistance, according Homa, in patients with chronic hepatitis C after supplementation with omega 3 fatty acids | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction of inflammatory cytokines (IL-1,IL-6, TNF) in patients with chronic hepatitis C after supplementation with omega 3 fatty acids | — |
Countries
Brazil
Contacts
Public ContactThiago Freire
Universidade Federal da Bahia
Outcome results
None listed