Open Angle Glaucoma
Conditions
Interventions
Randomized clinical trial comparing a conventional Selective Laser Trabeculoplasty (cSLT) protocol with an enhanced protocol (eSLT) and transscleral application (tSLT) in patients with open-angle glau
1.4 mJ in eyes with mild to moderate pigmentation). Regarding the application method, the application will be performed directly (transscleral) under the limbus.
Sponsors
Universidade Federal de São Paulo
Universidade Federal de São Paulo
Eligibility
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Age over 40 yo; Both sexes; Clinical indication for bilateral SLT; Diagnosis of ocular; hypertension or open angle glaucoma (mild to moderate); Open angle on gonioscopy; Baseline intraocular pressure equal to or greater than 16 mmHg
Exclusion criteria
Exclusion criteria: Gonioscopy alterations; Previous intraocular surgery or laser; History of ocular trauma; Advanced OAG; Other types of glaucoma; Associated ophthalmological diseases; Unreliable data; Participants in other clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to observe reduction above 20% compared to the initial intraocular pressure measured by Goldmann applanation tonometer after treatment with SLT;It is expected to observe reduction of one or more medications compared to the initial therapy after SLT | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluate the occurence of adverse events in the postoperative period of SLT;Observe the presence of endothelial alterations in specular microscopy after SLT;Evaluate quality of life assessment associated to the treatment with SLT;Assessment of predictors of success to the treatment with SLT | — |
Countries
Brazil
Contacts
Public ContactIsabela Valle
Universidade Federal de São Paulo
Outcome results
None listed