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Dental Sensitivity to in-office bleaching after use of a new Ibuprofen Nanogel

Sensitivity to in-office bleaching by application of a new Ibuprofen Nanogel

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
REBEC
Registry ID
RBR-4ng46xj
Enrollment
Unknown
Registered
2024-03-18
Start date
2024-03-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental sensitivity

Interventions

The bleaching procedure will be carried out by a single blinded researcher. After applying the protective gingival barrier to the buccal surfaces of the teeth (elements fifteen to twenty five and thir

Sponsors

Universidade Federal do Rio Grande do Norte
Lead Sponsor
Universidade Federal do Rio Grande do Norte
Collaborator

Eligibility

Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Be between 18 and 50 years old. Good general and oral health. Have at least 6 anterior teeth in the maxilla free of cavities and restorations and with color A2 or darker on the canine according to the VITA color scale classic never bleached before

Exclusion criteria

Exclusion criteria: Prosthesis users. Orthodontic appliance users. Patients with severe staining caused by tetracycline, fluorosis, trauma or teeth with pulp necrosis. Pregnant or breastfeeding women. Patients with bruxism, gingival recession, visible dentin exposure and cracks extensive. Patients with previous or current systemic health problems (stomach, heart, kidneys and liver), continuous users of anti-inflammatories and/or analgesics. Allergic to Ibuprofen or other components of the nanogel

Design outcomes

Primary

MeasureTime frame
To evaluate dental sensitivity through visual analog scale and numeric scale for 14 days after the first bleaching session

Secondary

MeasureTime frame
To evaluate color change through the Vitapan Classical Scale with bleached teeth extension

Countries

Brazil

Contacts

Public ContactJennifer Duarte

Universidade Federal do Rio Grande do Norte

jenniferduarte.ufrn@gmail.com+55 (84) 99493-8741

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 5, 2026