Chronic Obstructive Pulmonary Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Volunteers with the diagnosis of Chronic Obstructive Pulmonary Disease; who had inspiratory muscle weakness (70% of predicted maximal inspiratory pressure); with absence of heart failure; with stable pharmacological treatment; and with no comorbidity such as type 2 diabetes mellitus and hypertension.
Exclusion criteria
Exclusion criteria: Volunteers who had acute myocardial infarction three months before inclusion in the study; unstable ventricular arrhythmia or in the last three months before onset; acute respiratory disease; rheumatic diseases; degenerative diseases; neurological sequelae and cognitive deficit
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of 10% of maximal inspiratory and expiratory capacity and increase of forced vital capacity by 10%, measured by spirometry ;In the treatment group, an increase of 35% in inspiratory capacity and 28% in maximal expiratory pressure was found. Also, an 9% reduction in forced vital capacity was found. | — |
Secondary
| Measure | Time frame |
|---|---|
| Exercise tolerance, demonstrated by a 10% increase in the 6-minute Walk Test distance;In the treated group, a 32% increase in distance from the six-minute walk test was found.;Improved autonomic modulation, demonstrated by heart rate variability, with increased total variance of 20%;In the treated group, a 63% increase in total variance was found. | — |
Countries
Brazil
Contacts
Universidade Federal do Maranhão