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Effect of Inspiratory and Expiratory Training on autonomic modulation, exercise capacity and pulmonary capacity of Chronic Obstructive Pulmonary Disease patients

Influence of Respiratory Muscle Training on hemodynamic changes, pulmonary and autonomic diseases in patients with COPD

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4mz6w9
Enrollment
Unknown
Registered
2018-09-18
Start date
2016-05-02
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

During the experimental sessions, the 11 subjects in the inspiratory muscle training group remained seated in a comfortable chair. The exercise session consisted of 30 min (in a clinical setting) thre
Device

Sponsors

Universidade Federal do Maranhão
Lead Sponsor
Universidade Federal do Maranhão
Collaborator

Eligibility

Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Volunteers with the diagnosis of Chronic Obstructive Pulmonary Disease; who had inspiratory muscle weakness (70% of predicted maximal inspiratory pressure); with absence of heart failure; with stable pharmacological treatment; and with no comorbidity such as type 2 diabetes mellitus and hypertension.

Exclusion criteria

Exclusion criteria: Volunteers who had acute myocardial infarction three months before inclusion in the study; unstable ventricular arrhythmia or in the last three months before onset; acute respiratory disease; rheumatic diseases; degenerative diseases; neurological sequelae and cognitive deficit

Design outcomes

Primary

MeasureTime frame
Improvement of 10% of maximal inspiratory and expiratory capacity and increase of forced vital capacity by 10%, measured by spirometry ;In the treatment group, an increase of 35% in inspiratory capacity and 28% in maximal expiratory pressure was found. Also, an 9% reduction in forced vital capacity was found.

Secondary

MeasureTime frame
Exercise tolerance, demonstrated by a 10% increase in the 6-minute Walk Test distance;In the treated group, a 32% increase in distance from the six-minute walk test was found.;Improved autonomic modulation, demonstrated by heart rate variability, with increased total variance of 20%;In the treated group, a 63% increase in total variance was found.

Countries

Brazil

Contacts

Public ContactCristiano Mostarda

Universidade Federal do Maranhão

cristiano.mostarda@gmail.com+55-098-3272-8000

Outcome results

None listed

Source: REBEC (via WHO ICTRP)