Analgesia
Conditions
Interventions
This is a prospective, experimental, interventional, controlling, randomized and single blind study. The research will be carried out in a high complexity private hospital in São Luís do Maranhão. The
active bleeding
American Society of Anesthesiologists III, IV or V
history of hypersensitivity to drugs used in research
epilepsy
cardiac function functioning
severe surgery study
altered intracranial pressure or hemodynamic instability such as peripheral pressure 90%
systolic blood pressure 60mmHg and heart rate = 40 beats per minute. The sample size was calculations with an assumption of a possible difference of at least 30% in between the two groups. Therefore,
D27.505.696.277.350
Sponsors
Hospital São Domingos
Hospital São Domingos
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: After approval by the Research Ethics Committee of the Hospital and the Free and Informed Consent Term (APPENDIX C) signed, patients aged 18 to 65 years, ASA I-II, undergoing elective colonoscopy in a private hospital in São Luís - MA.
Exclusion criteria
Exclusion criteria: Patients who refuse to participate or who have: pregnancy, active gastrointestinal bleeding, ASA III-V, history of hypersensitivity to the drugs used in this research, epilepsy, severe heart failure, severe respiratory failure, increased intracranial pressure and /or hemodynamic instability such as peripheral oxygen saturation = 90%, systolic blood pressure (SBP) < 60 mmHg and heart rate = 40 bpm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find the best sedation scheme for coloscopy procedures through the method of comparing two proposed sedation schemes. Anesthesia time in minutes recorded as described above (before, during and after sedation) will be analyzed. Efficacy, safety and recovery time will be observed allowing at least a 5% variation in measurements before and after the intervention.;It is expected to find the best sedation scheme for coloscopy procedures through the method of comparing two proposed sedation schemes. Procedure time in minutes recorded as described above (before, during and after sedation) will be analyzed. Efficacy, safety and recovery time will be observed allowing at least a 5% variation in measurements before and after the intervention.;It is expected to find the best sedation scheme for coloscopy procedures through the method of comparing two proposed sedation schemes. Mean Arterial Pressure recorded as previously described (before, during and after sedation) will be analyzed. Efficacy, safety and recovery time will be observed allowing at least a 5% variation in measurements before and after the intervention.;It is expected to find the best sedation scheme for coloscopy procedures through the method of comparing two proposed sedation schemes. Heart rate will be analyzed in beats per minute recorded as described above (before, during and after sedation). Efficacy, safety and recovery time will be observed allowing at least a 5% variation in measurements before and after the intervention.;It is expected to find the best sedation scheme for coloscopy procedures through the method of comparing two proposed sedation schemes. Respiratory rate will be analyzed in breaths per minute recorded as described above (before, during and after sedation). Efficacy, safety and recovery time will be observed allowing at least a 5% variation in measurements before and after the intervention.;It is expected to find the best sedation scheme for coloscopy procedures throug | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find the best sedation scheme for coloscopy procedures through the method of comparing two proposed sedation schemes. Hemodynamic stability will be analyzed. The results will be observed and a variation of at least 5% in the measurements before and after the intervention will be allowed.;It is expected to find the best sedation scheme for coloscopy procedures through the method of comparing two proposed sedation schemes. Respiratory safety will be analyzed. The results will be observed and a variation of at least 5% in the measurements before and after the intervention will be allowed.;It is expected to find the best sedation scheme for coloscopy procedures through the method of comparing two proposed sedation schemes. Adverse effects will be analyzed. The results will be observed and a variation of at least 5% in the measurements before and after the intervention will be allowed.;It is expected to find the best sedation scheme for coloscopy procedures through the method of comparing two proposed sedation schemes. The duration of recovery from surgery will be analyzed. The results will be observed and a variation of at least 5% in the measurements before and after the intervention will be allowed.;It is expected to find the best sedation scheme for coloscopy procedures through the method of comparing two proposed sedation schemes. Pain control will be analyzed. The results will be observed and a variation of at least 5% in the measurements before and after the intervention will be allowed.;It is expected to find the best sedation scheme for coloscopy procedures through the method of comparing two proposed sedation schemes. Will be analyzed and satisfaction of patients and anesthesiologists with the procedure. The results will be observed and a variation of at least 5% in the measurements before and after the intervention will be allowed. | — |
Countries
Brazil
Contacts
Public ContactPlínio Leal
Hospital São Domingos
Outcome results
None listed