dyslipidemia, insulin resistance, inflammation, women
Conditions
Interventions
The 30 individuals will be randomly divided into two groups:
- Placebo Group (GP): composed of 15 individuals who will receive 4 capsules identical to those of the supplemented groups, containing 200m
Dietary supplement
G07.203.300.456.500
Sponsors
Universidade Federal de Goiás
Universidade Federal de Goiás
Eligibility
Sex/Gender
Female
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: The study population is composed of eutrophic women, aged between 20 and 50 years.
Exclusion criteria
Exclusion criteria: The exclusion criteria adopted for participation in this research will be: non-performance of all evaluations; participate in a food restriction program; Body Mass Index less than 18.5 kg / m2 and greater than 25 kg / m2; carriers of immune diseases, of hepatic or renal disease, hypo or hyperthyroidism, inflammatory and / or infectious diseases; lactose intolerant, in the use of anti-inflammatory drugs and / or antibiotics and / or immunosuppressants and / or nutritional supplements and / or insulin; chronic alcoholics; pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycemia will be determined by the enzymatic colorimetric method using the System Vitros Chemistry 950 Xrl automatic analyzer (Johnson & Johnson). The supplemented group is expected to show a reduction in blood glucose increase. The concentrations of LPS and LBP will be quantified from specific kits for use in ELISA microplate reader. A reduction in LPS and LBP concentrations in the supplemented group is expected.;Data not yet analyzed | — |
Secondary
| Measure | Time frame |
|---|---|
| The concentrations of total cholesterol, HDL-c, triacylglycerol, will be determined by the enzymatic colorimetric method using the System Vitros Chemistry 950 Xrl (Johnson & Johnson) automatic analyzer. The concentration of LDL-c will be calculated according to Friedewald's formula, for triacylglycerol values up to 400mg / dL, where LDL = CT-HDL-TG / 5 (FRIEDEWALD, LEVY, FREDERICKSON, 1972). As reference values for the lipid profile will be used those proposed by the IV Brazilian Directive on Dyslipidemias and Prevention of Atherosclerosis Department of Atherosclerosis of the Brazilian Society of Cardiology (2007). A reduction in total and LDL cholesterol concentrations in the supplemented group is expected. | — |
Countries
Brazil
Contacts
Public ContactAline Gomes
Universidade Federal de Goiás
Outcome results
None listed