Laser Therapy
Conditions
Interventions
This is a randomized clinical trial in which 80 patients will be included. All participants will receive instructions on oral hygiene (including the use of a toothbrush, dental floss, and toothpaste—a
E02.594.540
Sponsors
Centro Universitário do Pará - CESUPA
Centro Universitário do Pará - CESUPA
Eligibility
Age
6 Years to 18 Years
Inclusion criteria
Inclusion criteria: Patients aged between 6 and 18 years; of both genders; diagnosed with Acute Lymphoblastic Leukemia; undergoing Methotrexate treatment during the consolidation phase; following the Berlin-Frankfurt-Münster (BFM) 2012 protocol (5 g/m² over 24 hours by intravenous infusion), at the Oncology Department of the Octávio Lobo Children’s Oncology Hospital; patients or legal guardians who agree to and sign the Informed Consent Form
Exclusion criteria
Exclusion criteria: Presence of photosensitivity; loss of treatment follow-up; inability to complete the Visual Analogue Scale; refusal to undergo any Photobiomodulation session; and limitation in mouth opening
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the efficacy of Extraoral Light-Emitting Diode (LED) therapy in the prevention of Oral Mucositis associated with Methotrexate (MTX) treatment in children with Acute Lymphoblastic Leukemia (ALL). | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the efficacy of Extraoral Light-Emitting Diode (LED) therapy and Intraoral Light Amplification by Stimulated Emission of Radiation (LASER) therapy in the prevention of Oral Mucositis associated with Methotrexate (MTX) treatment in children with Acute Lymphoblastic Leukemia (ALL). | — |
Countries
Brazil
Contacts
Public ContactGiovana Okajima Carrenho
Centro Universitário do Pará - CESUPA
Outcome results
None listed