Oral contraceptives
Conditions
Interventions
Two groups will be selected. The initial intervention group will have 6 participants who will perform a high intensity interval training on a treadmill, with weekly frequency of 2 times a week and a t
Other
G11.427.410.698.277
Sponsors
Grupo Nobre de Ensino Ltda.
Escola Bahiana de Medicina e Saúde Pública
Eligibility
Sex/Gender
Female
Age
20 Years to 30 Years
Inclusion criteria
Inclusion criteria: Sedentary women; nulliparous; continued use of combined oral contraceptives for 6 months or more, aged 20 to 30 years.
Exclusion criteria
Exclusion criteria: Hepatic Impairment; diabetes; thyroid dysfunctions; kidney diseases; use of anabolics; alcoholism; smoking; corticoids; use of lipid lowering agents; diuretics; beta-blockers; obesity; polycystic ovary syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint 1: Lipid profile optimization with total cholesterol reduction; triglycerides; LDL cholesterol; non-HDL cholesterol and VLDL cholesterol in at least 20% of baseline values, calculated in mg / dL. ;Primary endpoint 2: Optimization of the inflammatory profile by the reduction of high sensitivity CRP in at least 20% of the baseline values, calculated in mg / L;Primary outcome 3: Increase in maximal oxygen uptake expressed by the distance covered in the Cooper protocol by at least 30% of baseline values, calculated in meters. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome 1: Reduction of renin levels; aldosterone and angiotensin converting enzyme in at least 20% of the baseline values, calculated as uUI / mL, ng / dL and U / L respectively. ;Secondary outcome 2: Reduced glucose levels and insulin in at least 20% of the baseline values, calculated in mg / dL and ?IU / mL respectively. | — |
Countries
Brazil
Contacts
Public ContactVinicius Gomes
Escola Bahiana de Medicina e Saúde Pública
Outcome results
None listed