Chronic Kidney disease in final stage
Conditions
Interventions
Inspiratory muscle training group (IMTG): 10 volunteers performed 3 sets of 15 breaths with 50% resistance of maximal inspiratory pressure with threshold IMT, for 24 sessions in the first hour of hemo
Aerobic training group (ATG): 10 volunteers performed exercise in cycle ergometer for 30 minutes, with pedaling cadence of 50 rpm, while maintaining the perceived effort of 3-7 (modified Borg scale),
Combined training group (CTG)
11 volunteers performed inspiratory muscle training before aerobic training by 24 sessions, following the protocols described for IMTG and ATG, respectively, in the first two hours of hemosialysis. Be
Other
G11.427.590.530.698.277
E02.779.474
Sponsors
Universidade Federal dos Vales do Jequitinhonha e Mucuri
Universidade Federal dos Vales do Jequitinhonha e Mucuri
Eligibility
Age
18 Years to 78 Years
Inclusion criteria
Inclusion criteria: Were included patients with chronic kidney disease on hemodialysis for longer three months and weekly frequency of three times a week; hemodialysis access by arterio-venous fistula.
Exclusion criteria
Exclusion criteria: Systolic blood pressure greater than 180 mmHg or diastolic blood pressure greater than 120 mmHg, ischemic heart disease, recent myocardial infarction (less than 6 months), complex ventricular arrhythmia, aortic stenosis, severe metabolic disease, severe anemia and aortic aneurysm; respiratory diseases, neurological or musculoskeletal that compromises the protocol execution; inability to perform any stage of protocol; absence in three consecutives exercise sessions; changes of clinical treatment during study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increased functional capacity, evaluated by the Shuttle Walk Test of 12 stages, held on a flat course 10 meters, delimited by two cones. The walking speed of the volunteers is determined by a sound stimulus being initiated to 0.5 m / s, with progressions of 0.17 m / s each minute (stages). Functional capacity was represented by the distance covered on the test and was considered an improvement, increase by more than 70m after the interventions, which are: inspiratory muscle training (IMTG), aerobic training (ATG), and combined training (CTG). There were significative differences of distance on SWT in all groups, compared to before control and after control/before interventions times (p < 0.001). The increase were of 118.4m (IC95% 9.5 - 227.4), 102.6m (IC95% 25.4 - 179.7) and 129.6m (IC95% 79.2 - 180.1), in GTMI, GTA e GTC, respectivelly. There were no differences between groups and after control periods. ;Increase of the inspiratory strenght, through the maximal inspiratory pressure (MIP) assessment by analogic manovacumoeter. In seated position and with nasal clip, the MIP of volunteers were assessed from residual volume. The highest value of three valid measurements was considered to analysis. Increases of 10cmH2O after interventions were considered improvement. There were significative differences of MIP in all groups, compared to before control and after control/before interventions times(p < 0.001). The increases were of 38.0cmH2O (IC95% 29.3 – 46.7) after IMTG. This increase was higher than that of the ATG (35.9m (IC95% 27.3 – 44.5) cmH2O; p = 0.047) and with no differences to the CTG (35.9cmH2O (IC95% 25.6 - 46.2). There were no differences during control period.;The lower limbs strength, assessed by the Sit-to-Stand test of 30 seconds. Volunteers were instructed to stand up completely from a 45 cm chair and sit down as quickly as possible until the volunteer touched the back on the backrest, with no support from the upper limbs. The number of full movements | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected. | — |
Countries
Brazil
Contacts
Public ContactPedro Henrique Figueiredo
Universidade Federal dos Vales do Jequitinhonha e Mucuri
Outcome results
None listed