Skip to content

How the carotid artery reacts to mental stress: a new test to assess blood vessel health

Carotid artery reactivity to mental stress: a potential new test for assessing vascular function

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4hrvmkb
Enrollment
Unknown
Registered
2025-07-07
Start date
2023-10-10
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abnormal results of cardiovascular function studies

Interventions

This is a randomized, crossover experimental clinical study. Population: 22 young adult individuals, both men and women, aged between 18 and 40 years
with no history of cardiovascular or metabolic diseases, infectious or inflammatory processes
with no history of cognitive deficits
waist-to-height ratio less than 0.5
non-smokers
individuals who do not use medications that may influence the analyzed variables
individuals who are neither very active nor sedentary
women without intrauterine devices. The assessments were conducted in the morning, with a fasting period of at least 6 hours for food, abstention from physical activity for 24 hours, and abstention fr
E05.318.370.150

Sponsors

Universidade Federal de Santa Catarina
Lead Sponsor
Universidade Federal de Santa Catarina
Collaborator

Eligibility

Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Young adult men and women; between 18 and 40 years old

Exclusion criteria

Exclusion criteria: Participants who reported a history of cardiovascular or metabolic diseases, infectious or inflammatory processes; people with a history of cognitive deficit; waist-to-height ratio greater than 0.5; smokers; people who used drugs that could influence the variables analyzed; very active or sedentary people; women with an intrauterine device

Design outcomes

Primary

MeasureTime frame
It is expected that mental stress will induce carotid artery reactivity, evidenced by the change in the percentage of dilation, similar to cold stress

Secondary

MeasureTime frame
It is expected to verify the reactivity of hemodynamic and autonomic modulation to mental stress, verified by changes in blood flow in the carotid artery, heart rate and cardiac pulse interval

Countries

Brazil

Contacts

Public ContactFrancisco Johann Fensterseifer

Universidade Federal de Santa Catarina

cardiovasc.ccb@contato.ufsc.br+55-48-37212880

Outcome results

None listed

Source: REBEC (via WHO ICTRP)