Radiotherapy session
Conditions
Interventions
This is a blind randomized clinical trial with the aim of evaluating the effect of two weekly irradiations of photobiomodulation (PBM) with low-intensity laser on the development of mucositis in patie
E02.594.540
Sponsors
Universidade Federal do Amazonas
Fundação Centro de Controle de Oncologia do Estado do Amazonas
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients aged 18 years or over; with a definitive diagnosis of head and/or neck cancer (lip, oral cavity and pharynx) determined by biopsy; who have started antineoplastic therapy no more than 24 hours before the first laser irradiation; whose antineoplastic treatment will consist of a total dose of RT 70 Gy, with a minimum dose of 50 Gy administered and chemotherapy with cisplatin weekly (30 to 40 mg/m2) and every 21 days (100 mg/m2)
Exclusion criteria
Exclusion criteria: Patients previously irradiated in the head and neck region; patients with metastasis; patients with any interruption of treatment; patients who are unable to attend appointments; patients undergoing unilateral irradiation of the head and neck; patients undergoing surgical resection of the facial nerve and/or its branches; patients with trismus
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to observe an Incidence of Mucositis Grades 3 and 4 not lower than the control group | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find a pain intensity and improvement in quality of life not inferior to the control group | — |
Countries
Brazil
Contacts
Public ContactErivan Gualberto Júnior
Universidade Federal do Amazonas
Outcome results
None listed