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Comparative study of laser treatments for intraocular pressure control in patients with glaucoma

Comparative study of Selective Laser Trabeculoplasty versus Laser Micropulsed Trabeluloplasty for Intraocular Pressure Control in Patients with Primary Open Angle Glaucoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-4h3xvg5
Enrollment
Unknown
Registered
2021-08-31
Start date
2016-07-07
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

In this retrospective study, 98 patients with uncontrolled Primary Open Angle Glaucoma (POAG) were submitted either to Selective Laser Trabeculoplasty or Micropulse Laser Trabeculoplasty. Two groups

Sponsors

RR Clínica Oftalmológica Ltda
Lead Sponsor
União Metropolitana de Educação e Cultura
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Primary Open Agle Patients on medical treatment (drops) in need to adjunctive intra-ocular pressure treatment to reach target pressure

Exclusion criteria

Exclusion criteria: Glaucoma patients with clinical diagnosis other than Primary Open Angle Glaucoma; advanced visual field defects; patients who had already undergone laser or fistulizing surgery for glaucoma control; history of ocular surgery within 6 months or prior laser to treatment or during 12-month follow-up period after the procedure; history of trauma and concurrent use of systemic or topical steroids and patients with corneal conditions precluding adequate laser treatment. In cases where both eyes were eligible we included only eye with higher baseline intraocular pressure

Design outcomes

Primary

MeasureTime frame
We observed a significant reduction in mean intraocular pressures in both groups at 1, 3, 6 and 12 months, compared to baseline. No statistically significant difference in mean intraocular pressure values were seen between groups at follow-ups, however a significantly higher number of medications was required in the Micropulsed Laser Trabeculoplasty group at 12 months (p<0.05), to achieve intraocular pressure levels considered treatment success

Secondary

MeasureTime frame
We found that structural parameters (Ocular Coherence Tomography, mean retinal nerve fiber layer thickness) and functional measurements (Visual Field, mean deviation) remained stable at the end of the study period, in both groups.

Countries

Brazil

Contacts

Public ContactRoberto Pimentel
rlauande2003@yahoo.com.br+5571 91863005

Outcome results

None listed

Source: REBEC (via WHO ICTRP)