Glaucoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Primary Open Agle Patients on medical treatment (drops) in need to adjunctive intra-ocular pressure treatment to reach target pressure
Exclusion criteria
Exclusion criteria: Glaucoma patients with clinical diagnosis other than Primary Open Angle Glaucoma; advanced visual field defects; patients who had already undergone laser or fistulizing surgery for glaucoma control; history of ocular surgery within 6 months or prior laser to treatment or during 12-month follow-up period after the procedure; history of trauma and concurrent use of systemic or topical steroids and patients with corneal conditions precluding adequate laser treatment. In cases where both eyes were eligible we included only eye with higher baseline intraocular pressure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We observed a significant reduction in mean intraocular pressures in both groups at 1, 3, 6 and 12 months, compared to baseline. No statistically significant difference in mean intraocular pressure values were seen between groups at follow-ups, however a significantly higher number of medications was required in the Micropulsed Laser Trabeculoplasty group at 12 months (p<0.05), to achieve intraocular pressure levels considered treatment success | — |
Secondary
| Measure | Time frame |
|---|---|
| We found that structural parameters (Ocular Coherence Tomography, mean retinal nerve fiber layer thickness) and functional measurements (Visual Field, mean deviation) remained stable at the end of the study period, in both groups. | — |
Countries
Brazil