Schizophrenia
Conditions
Interventions
Cognitive training will be conducted using 3 selected tasks from the standard instrumental enrichment program 1, which will involve: Point Organization (an activity aimed at developing the projection
Spatial Orientation 1 (aiming to develop the practice of using internal references – right, left, front, back – for orientation in space and in relation to people and objects)
and Analytical Perception (an activity whose objective is to develop the ability to divide the whole into parts (differentiation) and bring parts together into a whole (integration). All patients will
Sponsors
Universidade Federal de São Paulo
Universidade Federal de São Paulo
Eligibility
Inclusion criteria
Inclusion criteria: The patient must be clinically stable according to medical criteria and undergoing antipsychotic medication treatment; following the first psychotic episode; having been diagnosed with schizophrenia; in accordance with the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition; the psychiatric diagnosis will be confirmed using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders Fifth Edition; be between 18 and 40 years of age; have a minimum estimated IQ of 70; be capable of signing the informed consent form
Exclusion criteria
Exclusion criteria: Inability to communicate sufficiently in Portuguese to undergo the tests and participate in cognitive intervention; present any underlying organic or neurological condition affecting cognition; such as neurological injuries or seizures or traumatic brain disorders; diagnosis of intellectual disability IQ less than 70; chemical dependence or substance abuse including alcohol and drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Aiming to investigate the effectiveness of the instrumental enrichment program on the functionality of patients with schizophrenia after the first psychotic episode, using the Goal Attainment Scaling (GAS). We anticipate observing improvements in the functional life of patients following the completion of cognitive training sessions. | — |
Secondary
| Measure | Time frame |
|---|---|
| To analyze the effects of the intervention on cognitive and clinical variables. Cognitive variables, including attention, learning potential, and executive functions, will be assessed using the consensus cognitive battery MATRICS. Clinical variables, encompassing general psychopathology, will be evaluated through the total score on the Positive and Negative Syndrome Scale - PANSS. It is expected that improvements will be observed in the MATRICS cognitive battery scores, and clinical enhancements will be measured by the PANSS. | — |
Countries
Brazil
Contacts
Public ContactAna Olívia Montebelo
Universidade Federal de São Paulo
Outcome results
None listed