Arginine Vasopressin
Conditions
Interventions
This is a two-arm, open-label, randomized clinical trial. Randomized clinical trial carried out in a clinical analysis laboratory in northern Paraná. The study will include 40 healthy volunteers (20 v
VS2.001.001.002.002
B01.875.800.575.912.250.583.520.483
Sponsors
Universidade Estadual de Londrina
Universidade Estadual de Londrina
Eligibility
Sex/Gender
Male
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Age between 18 and 50 years; male, not be smoker; not be alcoholic; daily fluid intake habits: minimum of 2 liters of water / day
Exclusion criteria
Exclusion criteria: Kidney failure; systemic arterial hypertension; diabetes; hydroelectrolytic disorders such as vomiting and diarrhea; women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the efficacy of the mentholated popsicle compared to usual care in healthy volunteers, about the plasma vasopressin. A randomized clinical trial, in parallel, with two groups: control group and experimental group. It will be considered the level if significance of 5% and confidence interval of 95%. To test the effect of mentholated popsicles ANOVA will be used according to the multivariate model. It is expected to observe a reduction profile vasopressin when receiving mentholated popsicle. | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare plasma vasopressin, osmolarity, intensity, discomfort of thirst and oral dehydration, after receiving the mentholated popsicle in relation to usual care. A randomized clinical trial, in parallel, with two groups: control group and experimental group. It will be considered the level if significance of 5% and confidence interval of 95%. The normality distribution of the urinary osmolarity variable will be determined by the Shapiro-Wilk test, later it will be evaluated using the Student's t test. To test the effect of mentholated popsicles in the five on intensity, discomfort, concentration of osmolarity and intramural oral moisture, one-way ANOVA will be used according to the multivariate model. It is expected to observe a reduction in the intensity and discomfort of thirst, as well as an improvement in oral intramucosal moisture. | — |
Countries
Brazil
Contacts
Public ContactThammy Nakaya
Universidade Estadual de Londrina
Outcome results
None listed