Effects of Photodynamic Therapy as aid on non-surgical treatment of Aggressive Periodontitis

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

REBEC

Registry ID

RBR-4gq6khr

Enrollment

Unknown

Registered

2020-12-10

Start date

2020-12-16

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aggressive Periodontitis

Interventions

Group 1 (control): Scraping and root planing + full mouth disinfection + amoxicillin 500 mg and metronidazole 400 mg 8/8 hours 14 days

Group 2 (test 1): Scraping and root planing + full mouth disinfection + amoxicillin 500 mg and metronidazole 400 mg 8/8 hours 14 days 1 + photodynamic therapy 1 session

Group 3 (test 2): Scraping and root planing + full mouth disinfection + amoxicillin 500 mg and metronidazole 400 mg 8/8 hours 14 days 1 + photodynamic therapy 4 sessions

Group 4 (test 3): Scraping and root planing + full mouth disinfection + amoxicillin 500 mg and metronidazole 400 mg 8/8 hours 14 days 1 + infrared application 4 sessions.

E02.186.500

Eligibility

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Individuals between 18 and 40 years old with a clinical diagnosis of Aggressive periodontitis, according to the American Academy of Periodontics (1999) or Periodontitid satages III or IV grade C; Presence of at least 8 teeth with PS > 5 mm and CIN ? 5 mm, 2 teeth per quadrant; Agree to participate in the survey by signing the informed consent form

Exclusion criteria

Exclusion criteria: Pregnant and lactating women; Carriers of systemic diseases that compromise the immune system; Unable to answer the questionnaires or perform the tests or treatment; Allergic to Amoxicillin, Metronidazole, Chlorhexidine or Photosensitizer;Those who underwent periodontal therapy less than 6 months ago.

Design outcomes

Primary

Measure	Time frame
Primary Outcome: Changes in Clinical Attachment Level (CAL) in periodontal clinical evaluation following treatment with antimicrobial photodynamic therapy in patients with Aggressive Periodontitis.	—

Secondary

Measure	Time frame
Secondary Outcome: Changes, after antimicrobial photodynamic therapy, in the other parameters observed in the periogram (Gingival Bleeding Index, Bleeding on Probing, Gingival Recession and Probing Depth), as well as changes in microbiological evaluations gingival sulcus), immunological (inflammatory cytokines in gingival fluid and tissue), radiographic (bone conformation and density), occlusal (static and dynamic parameters) and quality of life of individuals undergoing treatment.	—

Measure

Time frame

Secondary Outcome: Changes, after antimicrobial photodynamic therapy, in the other parameters observed in the periogram (Gingival Bleeding Index, Bleeding on Probing, Gingival Recession and Probing Depth), as well as changes in microbiological evaluations gingival sulcus), immunological (inflammatory cytokines in gingival fluid and tissue), radiographic (bone conformation and density), occlusal (static and dynamic parameters) and quality of life of individuals undergoing treatment.

—

Countries

Brazil

Contacts

Public ContactRaissa da Costa

raissaoa@hotmail.com+5584998010362

Outcome results

None listed

Source: REBEC (via WHO ICTRP)