Leiomyoma of uterus, abdominal hysterectomy, Nausea and Vomiting.
Conditions
Interventions
Patients will be randomly divided into 2 groups (65 patients in each group) according to the antiemetic prophylaxis used intraoperatively. Group 1 will receive intravenously 8mg of dexamethasone and 4
Drug
Sponsors
Hospital São Rafael
Hospital São Rafael
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: One hundred and thirty patients classified as American Society of Anesthesiologists (ASA) physical status 1 or 2; aged between 18 and 65 years.
Exclusion criteria
Exclusion criteria: Patients who received corticosteroids and antiemetic drugs in the 24 hours before the procedure; ASA physical status III or IV; allergy to medications involved in protocol; situations that contraindicate to perform spinal anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative nausea and vomiting in both groups. Patients will be inquired about the presence or absence of these symptoms at the intervals of 0-2h, 2-24h and 24-48h. The intensity of nausea is evaluated by visual analog scale (0: no 10: maximum), amd vomiting will be determined as present or absent, as the frequency of happening. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of itching and pain. Patients will be inquired about the presence or absence of these symptoms at the intervals of 0-2h, 2-24h and 24-48h. The intensity of pain and itching will be assessed by visual analog scale (0: no 10: maximum). | — |
Countries
Brazil
Contacts
Public ContactGuilherme Campos
Hospital São Rafael
Outcome results
None listed