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Proximetacaine anesthetic effect in the eyes: comparison between eyedrops in open eyes and vaporization in closed eyes

Anesthetic effect of Proximetacaine hydrochloride 0,5%: comparison between eyedrop instillation in open eyes and vaporization in closed eyes

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
REBEC
Registry ID
RBR-4gjhfk
Enrollment
Unknown
Registered
2018-09-25
Start date
2018-10-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ocular Hypertension

Interventions

Proximetacaine 0,5% eye drop instillation will occur in one of the eyes of 50 patients. In the other eye, vaporization with the same ophthalmic solution will be done. Each eye will receive a topical a
Drug

Sponsors

Universidade Estácio de Sá
Lead Sponsor
Universidade Estácio de Sá
Collaborator

Eligibility

Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Adult volunteers; both genders; consulted at the Policlinica Ronaldo Gazolla ophthalmological clinic; need to perform aplanation tonometry for intraocular pressure measurement.

Exclusion criteria

Exclusion criteria: volunteers with corneal disease; Refusal in signing the informed consent; Mentally retarded that does not understand research procedures.

Design outcomes

Primary

MeasureTime frame
30% esthesiometric corneal reduction with 0,5% proximetacaine spray administration in closed eyes, compared to eye drop aplication in open eyes. Esthesiometry measurement will be realized by a Cochet-Bonnet esthesiometer, before, 2, 5, 10 and 15 minutes after proximetacaine topical administration in each eye. The eyes will be selected for each aplication method according to a pseudoaleatory table of numbers. Immediately after anesthetic aplication, they will be submitted to aplanation tonometry.

Secondary

MeasureTime frame
Perceived difficulties and facility level about different ocular topical anesthetic administration methodos by questionnaire aplication. It is expected greater facility with vaporization. Evaluation of anesthetic adequacy aplication technique that will be observed by the authors.It is expected that both methods occur adequately Measurement of Anesthetic aplication time for each administration method. It is expected that spray aplication occur faster. Observation if aplanation tonometry was realized normally.

Countries

Brazil

Contacts

Public ContactArlindo Portes

Universidade Estácio de Sá

portes@uol.com.br+55999119955

Outcome results

None listed

Source: REBEC (via WHO ICTRP)