Rheumatoid Arthritis
Conditions
Interventions
Experimental group: 20 women with rheumatoid arthritis will receive intra-articular infiltration with 3 ml of triamcinolone hexacetonide in the knee. Control group: 20 women will receive 3ml of saline
Drug
D04.808.745.432.915
Sponsors
Universidade Estadual Paulista - UNESP
Faculdade de Medicina de Marília
Universidade Estadual Paulista - UNESP
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Diagnosis of RA according to the American College of Rheumatology (ACR) Classification Criteria of 1987 or Classification Criteria for RA 2010 of the ACR / EULAR; Age over 18 years; Female gender; Analog Visual Scale (EVA) of knee pain between 40 and 80 mm; EVA of knee edema between 40 and 80 mm; Be stable with drugs modifying the course of the disease in the last 3 months and / or oral corticosteroids in the last month; Presence of refractory knee injury in the last 3 months.
Exclusion criteria
Exclusion criteria: Injury and / or diseases symptomatic knee than RA; radiographic classification of Kellgren-Lawrence grade IV; Knee prosthesis in the target joint; prior realization of any IIAC in the last 6 months; Symptoms of systemic or local infection; reported hypersensitivity to the drug components or contraindication to the use thereof;Suspected or confirmed pregnancy; Physical therapy or other treatment in parallel to symptom in knee; Uncontrolled systemic arterial hypertension; Previous knee surgery to be evaluated; Skin lesions at the IIA site; Deficit vision or hearing or cognitive preventing the completion of the evaluations proposed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of the muscular strength of knee extensors after IIA verified by means of a load cell from the observation of a variation of at least 10% in the pre and post intervention measurements | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of pain and edema assessed through visual analogue scale; Improvement of functionality assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Health Assessment Questionnaire (HAQ), Lequesne's Algofunctional Questionnaire, 30-s chair-stand test , and Timed Up and Go Test; Improvement of range of motion assessed by computerized photogrammetry | — |
Countries
Brazil
Contacts
Public ContactMariana Lourenço
Universidade Estadual Paulista - UNESP
Outcome results
None listed