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Additional Effect of Transcutaneous Electrical Stimulation on the Efficacy of Inferior Alveolar Nerve Anesthesia in Irreversible Pulpitis: a randomized placebo-controlled clinical trial

Effect of Pain Inhibitory Modulation Techniques on Blockade Analgesic Efficacy Inferior Alveolar Nerve Anesthetic in Irreversible Pulpitis: A clinical trial randomized placebo controlled

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4fn5b4p
Enrollment
Unknown
Registered
2023-07-12
Start date
2019-06-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulpitis

Interventions

This is a randomized placebo-controlled clinical trial, where pain levels on a scale of 0 - 100 will be assessed during the endodontic treatment procedure in patients diagnosed with symptomatic irreve
E02.331

Sponsors

Faculdade de Odontologia de Bauru - Universidade de São Paulo
Lead Sponsor
Faculdade de Odontologia de Bauru - Universidade de São Paulo
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Clinical diagnosis of unilateral symptomatic irreversible pulpitis in mandibular premolars and molars

Exclusion criteria

Exclusion criteria: Allergy to ketorolac or the anesthetic used; history or presence of uncontrolled systemic diseases; chronic pain; neurological; hormonal; rheumatic; psychiatric disorders; pregnancy; lactation; pacemaker presence

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: It is expected to find improvement in analgesic efficacy and, therefore, to improve anesthesia of the inferior alveolar nerve during irreversible pulpitis therapy with a significance level of 5%.;Outcome found 1: It was observed that there was a 35% improvement in the analgesic efficacy of the inferior alveolar nerve block in the comparison between the active and placebo groups.

Secondary

MeasureTime frame
Expected outcome 2: An improvement in pain intensity is expected after the use of ketorolac 10mg, with a significance level of 5%.;Outcome found 2: It was observed that after using the drug ketorolac 10mg there was no statistical difference between the groups, but with an improvement in the level of pain of 75% on average, when compared to before and after using the drug.

Countries

Brazil

Contacts

Public ContactRenan Furlan

Faculdade de Odontologia de Bauru - SP

renan.furlan@usp.br+55 (18) 997056550

Outcome results

None listed

Source: REBEC (via WHO ICTRP)