Hypertension
Conditions
Interventions
Hypertensive men between 30 e 65 years old will be randomly divided in 4 groups that will train three tomes per week for 10 weeks
Group dynamic resistance training – 3 set o moderate fatigue at 50% of
Other
F01.145.632
Sponsors
Escola de Educação Física e Esporte da Universidade de São Paulo
Laboratório de Hipertensão do Hospital das Clínicas da Faculdade de Medicina da USP
Eligibility
Sex/Gender
Male
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: Men between 30 and 65 years old; with diagnosis of hypertension and under antihypertensive medication with drug and dose maintained at least in then previous 4 months; not taking anti-hypertensive drugs that directly affect cardiac autonomic regulation (such as beta-blockers and non-dihydropyridine calcium channels inhibitors); not practicing physical exercise more than twice a week or more than 150 minutes/week; no resistance exercise practice in the previous 6 months.
Exclusion criteria
Exclusion criteria: Presence of secondary hypertension and/or target-organ lesion; systolic/diastolic blood pressures equal to or greater than 160/105 mmHg; obesity level II or superior; other cardiovascular diseases besides hypertension; diabetes with complications or in use of insulin; presence of osteoarticular diseases that limit resistance exercise execution; electrocardiographic alterations during maximal exercise test that suggest cardiovascular diseases; change in dose or medication during the protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease of clinic blood pressure measured by auscultatory technique with a minimum reduction of 4 mmHg ;Decrease of ambulatory blood pressure measured by oscillometric technique with a minimum reduction of 3 mmHg;Decrease of exercise blood pressure measured by photoplethysmographic technique with a minimum reduction of 3 mmHg | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of cardiovascular autonomic modulation, as evidenced by the increase of heart rate variability, reduction of blood pressure variability and increase in baroreflex sensitivity measured with spectral analysis.;Improvement of the endothelial function verified by the flow-mediated dilation technique (FMD) with a minimum increase of 4% in artery diameter between the initial and final evaluations;Reduction in peripheral vascular resistance based on calculus considering the cardiac output measured by the CO2 rebreathing technique from a minimum 7% reduction between the initial and the final evaluations. | — |
Countries
Brazil
Contacts
Public ContactClaudia Forjaz
Escola de Educação Física e Esporte da Universidade de São Paulo - EEFEUSP
Outcome results
None listed