Osteoarthritis Knee
Conditions
Interventions
This is a two-arm, double-blind, randomized controlled clinical trial. Participant randomization will follow a table of random numbers generated using the electronic tool Research Randomizer. Experime
E02.331.800
G11.427.410.698.277
Sponsors
Universidade Federal de Alfenas
Universidade Federal de Alfenas
Eligibility
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: Male and female participants; age between 50 and 75 years; symptomatic knee osteoarthritis for at least 3 months; pain score greater than 3 on the 0–10 Numeric Rating Scale (NRS); Kellgren–Lawrence classification greater than grade 1
Exclusion criteria
Exclusion criteria: History of cancer; patients with type I diabetes; with uncontrolled arterial hypertension; with cardiac pacemaker; presenting neurological deficits; with orthopedic surgery in the lower limbs; with body mass index above 40 kg/m²; with symptomatic hip osteoarthritis; presenting cognitive impairment; with history of brain surgery; seizure; stroke or intracranial metal implantation; who underwent craniectomy at the site of transcranial direct current stimulation application; and decompensated ventricular shunt
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A variation in pain intensity is expected, measured by the Numerical Rating Scale (0 to 10), with a significant reduction in pain levels anticipated between pre- and post-intervention assessments | — |
Secondary
| Measure | Time frame |
|---|---|
| A decrease in functional limitation is expected, measured by the Lequesne Index (0 to 24 points), with a significant reduction in functional limitation levels anticipated between pre- and post-intervention assessments;An improvement in functional mobility is expected, assessed by the Timed Up and Go (TUG) test, considering that shorter execution times indicate better performance. A significant reduction in test completion time is anticipated when comparing pre- and post-intervention measurements;A decrease in the physical activity score (0 to 68) is expected, measured using the Western Ontario and McMaster Universities Arthritis Index (WOMAC), when comparing pre- and post-intervention results, considering that higher scores indicate lower levels of physical activity;An increase in muscle strength of the knee extensors and flexors is expected, assessed using a handheld dynamometer, when comparing pre- and post-intervention values, considering that higher values indicate improved muscle strength;An improvement in postural balance is expected, assessed using the Biodex Balance System (BBS), when comparing pre- and post-intervention values, considering that lower sway values indicate better postural control | — |
Countries
Brazil
Contacts
Public ContactAdriana Teresa Silva Santos Santos
Universidade Federal de Alfenas
Outcome results
None listed