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Risk factors for caries lesion development and progressionin adolescents

Incidence and Progression of Occlusal Caries in Adolescents - Risk Factors

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4dr59v
Enrollment
Unknown
Registered
2020-09-14
Start date
2015-03-07
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stomatognathic diseases

Interventions

Intervention 1 – Responsiveness of the Child Perception Questionnaire (CPQ11-14) to detect changes in oral-health-related quality of life (OHRQoL) and oral health status of adolescents enrolled in an
Procedure/surgery
Behavioural
Other
G10.549.140

Sponsors

Faculdade de Ciências da Saúde
Lead Sponsor
Faculdade de Ciências da Saúde
Collaborator

Eligibility

Age
10 Years to 16 Years

Inclusion criteria

Inclusion criteria: Students (10 to 16 years-old) with at least one permanent second molar partially erupted; students with permanent second molars erupted and in occlusion

Exclusion criteria

Exclusion criteria: Students with the permanent second molars partially erupted with sealants, fillings or cavities; students with the permanent second molars in occlusion with sealants, fillings or cavities;students with cronical diseases.

Design outcomes

Primary

MeasureTime frame
Expected outcome 1 To assess the influence of the heavy plaque and the stage of tooth eruption on the incidence and progression of occlusal caries in adolescents using univariate and multivariate analysis. The construct validity of the Visible Occlusal Plaque Index (VOPI) along with its sub-types, convergent and discriminant validity it would be tested. The VOPI was developed to assess the occurrence and distribution of dental biofilm on the groove-fossa system in relation to caries. The VOPI has a four point ordinal scale ranging from no plaque to heavy plaque. The sample size calculation was estimated based on an expected difference in caries incidence of 10% between adolescents with erupting and fully erupted second molars. Given a power of 80% and a confidence interval of 95%, 219 children in each group were required at the end of the study. Considering a dropout rate of 30% after 3 years of the clinical trial, 313 adolescents in each group were foreseen. The sufficiency of the sample size for validating the VOPI as a measure of the association between dental biofilm and caries lesion activity status was considered more than large enough. The incidence and progression of dental caries will be observed on the occlusal surface of the second molars. Dental status on the occlusal surfaces of the second molars partially erupted (test group) and fully erupted (control group) was verified in relation to both: 1- dental biofilm accumulation observed at each different occlusal sites and 2- the stage of tooth eruption. Analysis of fully erupted molars caries lesions were also performed. Methods: The Validation of the Visible Occlusal Plaque Index (VOPI) in estimating caries lesion activity to detect the occurrence and distribution of the dental biofilm on the different molars occlusal sites. The VOPI criteria varied from no visible plaque identified to heavy plaque on the occlusal surfaces partially or totally erupted molars (Carvalho et al. 1989). The criteri

Secondary

MeasureTime frame
Expected outcome 2 Socioeconomic status The questionnaire filled out by the parents inquired information about family sociodemographic variables which were reported in the following terms: mother’s level of education (technical or university, secondary schooling, primary schooling or less), employment status of the head of the family (employed, unemployed, retired or other), family monthly income (from 1 to 4 minimum wages, less than 1 minimum wage), size of the household (1–3 persons, 4 –6 persons, 7 or more persons), and car ownership (yes, no). This result was presented in terms of frequency at the baseline and after 12 months evaluation and also composed the multivariate analysis related to dental caries and oral health related quality of life. ;Outcome 2 Socioeconomic status The questionnaire filled out by the parents inquired information about family sociodemographic variables which were reported in the following terms: mother’s level of education (technical or university, secondary schooling, primary schooling or less), employment status of the head of the family (employed, unemployed, retired or other), family monthly income (from 1 to 4 minimum wages, less than 1 minimum wage), size of the household (1–3 persons, 4 –6 persons, 7 or more persons), and car ownership (yes, no). This result was presented in terms of frequency at the baseline and after 12 months evaluation and also composed the multivariate analysis related to dental caries and oral health related quality of life. ;Expected outcome 3 Oral higiene behavior Questionnaire concerning oral hygiene behaviors at the baseline, 12 and 24 months was applied. The frequency of tooth brushing, use of fluoride dentifrice and dental floss were analyzed. The results were presented in terms of frequency and included in multifactorial analysis related to the incidence and progression of dental caries, dental enamel erosion, dental fluorosis and oral health related quality of life. ;Outc

Countries

Brazil

Contacts

Public ContactHeliana Mestrinho

Fundação Universidade de Brasília

helianamestrinho@gmail.com+5561981790981

Outcome results

None listed

Source: REBEC (via WHO ICTRP)