Alzheimers disease
Conditions
Interventions
The study proposes to evaluate the microdosing effect of a Cannabis sativa extract rich in THC in patients with Alzheimer's Disease. The aim of the study is to assess the effects on cognitive symptoms
Sponsors
Universidade Federal da Integração Latino-Americana
Associação Brasileira de Apoio a Cannabis Esperança
Eligibility
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: 60 years old or older; to be diagnosed with Alzheimer for at least 1 year
Exclusion criteria
Exclusion criteria: to have diagnostic of other dementias or correlated diseases; família historic of psychosis; ilegal psychoactive drugs use
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We hope to find a significant improvement in the cognitive and memory parameters of patients, for this we will use the Mini-Examination of mental state and Adas-Cog tests that will be applied to patients and the DSRS cognition and memory test that will be applied to the caregiver. We expect a reduction in the scores of the indicated tests, reaching a degree of an individual without Alzheimer's disease and that during the 12 months that will be evaluated that these parameters remain stable | — |
Secondary
| Measure | Time frame |
|---|---|
| We expect an improvement in sleep quality and excessive daytime sleepiness in individuals with Alzheimer's disease;Improvement in neuropsychiatric symptoms, for this we will use the Neuropsychiatric Inventory, Cornell scale for depression in dementia and geriatric depression scale;Improvement in the quality of life in individuals with Alzheimer's Disease and their respective caregivers, we will use the questionnaire of quality of life in Alzheimer's Disease version patient and caregiver | — |
Countries
Brazil
Contacts
Public ContactFrancisney Nascimento
Universidade Federal da Integração Latino-Americana
Outcome results
None listed