Autonomic Nervous System disorders
Conditions
Interventions
This was a single-center, cross-sectional, observational study with a convenience sample, consisting of three groups of 30 women in each group, aged between 37 and 75 years. Experimental group 1: 30 f
Sponsors
Universidade de São Paulo
Instituto do Câncer do Estado de São Paulo
Eligibility
Sex/Gender
Female
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: Group 1 women; aged between 35 and 75 years; survivors of histologically proven invasive breast cancer; who completed treatment with curative intent including systemic chemotherapy; having completed treatment within a time interval of at least six months to four years; practicing physical exercises for at least 6 months as defined by the application of the international physical activity questionnaire (IPAQ); Group 2 women; aged between 35 and 75 years; survivors of histologically proven invasive breast cancer; who completed treatment with curative intent including systemic chemotherapy following the recommended guidelines; having completed treatment within a time interval of at least six months to four years; without regular practice of physical exercises in the last 6 months as defined by the application of the International international physical activity questionnaire (IPAQ); Group 3 women; aged 35-75 years; without a diagnosis of cancer; non-practitioners of systematic physical exercise on a regular basis in the last 6 months as defined by the application of the international physical activity questionnaire (IPAQ)
Exclusion criteria
Exclusion criteria: Group 1: evidence of metastatic disease (clinical and/or radiological) and/or conditions that prevent them from practicing physical exercise; severe organic dysfunctions (including, but not limited to, kidney failure, heart failure and chronic liver disease); previous cognitive dysfunction and (or) dysautonomia; presence of any medical contraindication to physical exercise; not being involved in any systematic exercise practice on a regular basis in the last 6 months.Group 2: evidence of metastatic disease (clinical and/or radiological) and/or conditions that prevent them from practicing physical exercise; severe organic dysfunctions (including, but not limited to, kidney failure, heart failure and chronic liver disease); previous cognitive dysfunction and (or) dysautonomia; presence of any medical contraindication to physical exercise; being involved in some systematic exercise practice on a regular basis in the last 6 months. Group 3: history of cancer treatment; presence of autonomic dysfunctions, cardiovascular problems, diagnosis of neurological diseases with cognitive involvement and presence of conditions that prevent them from practicing physical exercise; report of practicing systematic physical exercises, regularly, in the last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate, using the battery of Ewing autonomic tests and the analysis of heart rate variability, whether women survivors of breast cancer, who have experienced classic antineoplastic treatment, with chemotherapy, present autonomic changes resulting from the toxicity of this treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| By carrying out cognitive tests and autonomic analysis tests, it is expected to find a possible association between autonomic changes and perceived cognitive impairment in women who are breast cancer survivors;Through tests of physical functionality, physical fitness level and the IPAQ questionnaire, the aim is to evaluate whether women survivors of breast cancer who have undergone chemotherapy treatment and who have more active lifestyle patterns, can present better autonomic balance scores and preservation of cognitive variables;We will observe, through the application of the QLQ30 and DASS21 questionnaires, whether female breast cancer survivors who have undergone chemotherapy and are physically active have better quality of life scores, when compared to female breast cancer survivors who have experienced the same treatment and are not exercisers | — |
Countries
Brazil
Contacts
Public ContactPatricia Brum
Universidade de São Paulo
Outcome results
None listed