Hypertension
Conditions
Interventions
Patients will be randomized 1:1 to intervention or control groups. through the randomizer software. The randomization sequence will be generated using a random number generator. Due to the nature of t
ii. elaboration of the care plan and iii. evaluation of results. Patients will be followed up for one year and the pharmacist will carry out six consultations, with an interval of two months between e
Sponsors
Universidade Federal do Espírito Santo
Universidade Federal do Espírito Santo
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with age 18 years or older; diagnosis of Hypertension according to the criteria of the Brazilian Guideline of arterial hypertension; use at least one medication for Hypertension for at least six months; purchase at least one medication for Hypertension at the community pharmacy in the municipality of Alegre/ES in the last six months.
Exclusion criteria
Exclusion criteria: patients with plans to move from the municipality during the study period; people who do not have autonomy over their health and use of their own medicines; pregnant women, women with the intention of becoming pregnant during the execution of the study and/or lactating women; patients with terminal disease (eg terminal cancer; chronic kidney disease on dialysis); individuals who do not attend three consecutive pharmaceutical consultations; patients treated by other clinical pharmacy services; patients with a history of myocardial infarction or stroke in the last six months; individuals who are participating in other studies that assess impacts of health interventions on cardiovascular parameters and glycemic control.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical: Proportion of patients who achieved blood pressure control and reduction in baseline systolic blood pressure and diastolic blood pressure Blood pressure will be measured at three times (T0, T6, T12), as recommended by the Brazilian Hypertension Guideline (Barroso et al., 2021), using the Omron device - Automatic Arm Blood Pressure Monitor, model HEM- 7320.;Humanistic: Proportion of patients who have improved quality of life. This outcome will be evaluated using the European Quality of Life 5 dimensions questionnaires (EQ-5D) and Mini-questionnaire for Quality of Life in Arterial Hypertension (MINICHAL) (MOHAMMED & UMESH, 2020; SANTOS et al.; 2016; SCHULZ et al., 2008) aThe EQ-5D is a generic questionnaire applied to various health conditions, validated for Brazil (SANTOS et al., 2016). This questionnaire consists of two parts: a descriptive system, with five dimensions: mobility, personal care, usual activities, pain/discomfort, anxiety/depression, each with 3 levels of severity and a visual analogue scale, which ranges from zero (worst imaginable health state) to 100 (best imaginable health state). The MINICHAL is a specific questionnaire for hypertension and contains 17 multiple-choice questions organized into two factors: Mental Status (10 questions), Somatic Manifestations (6 questions), in addition to a question to verify how the patient evaluates that hypertension and its treatment have influenced their quality of life (SCHULZ et al., 2008). ;Economical: direct medical costs Estimating the costs will involve three steps: (1) defining the analysis perspective and the costs relevant to the evaluation, (2) measuring the resources used, and (3) valuing the resources. (1) The perspective of the analysis will be that of the public funder of health services. In this case, the perspective of the Braziliam Health System (SUS) will be adopted. (2) The measurement of costs will be carried out through a specific questionnaire delimited for this purpose. (3) The | — |
Secondary
| Measure | Time frame |
|---|---|
| Knowledge of patients about their medications: The MedTake test will be used to assess patients' knowledge of prescribed medications (RAEHL, 2002). This instrument addresses the following domains: dose, indication, interaction with food and medication intake scale. Each patient's correct answer on these domains corresponds to 25% of knowledge about the drug. Therefore, for each drug prescribed, the patient may receive a score from 0% to 100%.;Patient knowledge about hypertension: The patient's knowledge about hypertension will be assessed using the Hypertension Knowledge-Level Scale (HK-LS) instrument, developed by Ercok et al. (2012). This instrument was translated, cross-culturally adapted to Brazilian Portuguese and has evidence of reliability, validity of content, appearance, construct and criteria to measure knowledge about hypertension in Brazilians (Arthur et al., 2018; Hereibi et al., 2021). The HK-LS has 22 statements divided into six sub-dimensions: definition (items 1 and 2); medical treatment (items 6, 7, 8 and 9); medication adherence (items 3, 4, 5 and 12); lifestyle (items 10, 11, 13, 16 and 17); diet (items 14 and 15); and complications (items 18, 19, 20, 21 and 22). Each statement is answered using a Likert scale, with three response options: right, wrong and I don't know, and the maximum scale score is 22 points.;Medication Adherence: Medication Adherence will be measured using the Adherence to Refills and Medications Scale (ARMS) instrument, developed by Kripalani and collaborators (2009) and translated and validated into Brazilian Portuguese by Aguiar (2019). This instrument provides an accurate assessment of the behavior of patients in relation to the use of medicines in a population with low literacy and chronic disease and it proved to be valid and reliable, having high internal consistency (AGUIAR, 2019; KRIPALANI et al., 2009). The ARMS scale is composed of 12 questions, which aim to assess medication intake and replacement. Each item is com | — |
Countries
Brazil
Contacts
Public ContactGenival Santos Júnior
Universidade Federal do Espírito Santo
Outcome results
None listed