Tremor Parkinson Disease
Conditions
Interventions
This is an interventional, randomized study comparing two conditions: without the use of a compressive band and with the use of a compressive band on the upper limb.The study sample will consist of 10
Sponsors
Faculdade de ciências médicas - Universidade de Pernambuco
Escola Politécnica - Universidade de Pernambuco
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Diagnosis of Parkinson’s disease; Presence of tremor in the upper limb; Age 18 years or older; People of any sex; Mild to moderate disease progression, corresponding to stages 2 and 3 according to the modified Hoehn and Yahr classification; Absence of cognitive impairment, based on data collected from medical records and/or a Mini-Mental State Examination (MMSE) score greater than 24 points for literate individuals and greater than 17 points for illiterate individuals or those with low educational attainment, when this information was not available in the patient’s medical record; Absence of peripheral nervous system disorders
Exclusion criteria
Exclusion criteria: Presence of other neurological disorders that limit movement; History of injuries affecting proprioceptive sensitivity; Fragile and atrophic skin, dermatoporosis, at the sites where compression would be applied; Inability to follow the study instructions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess tremor amplitude and the pressure applied to the most affected upper limb. The outcome was measured using an MPU-6050 inertial sensor positioned on the dorsal region of the hand, and FSR402 resistive membrane pressure sensors positioned over the arm extensor muscles and the muscles related to forearm pronation and supination movements. Tremor amplitude and applied pressure values were analyzed under the conditions without and with the compressive band, observing a reduction in tremor amplitude in the compression condition compared with the no-compression condition. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the functional level of participants with Parkinson’s disease. The outcome was measured using sections II and III of the Unified Parkinson’s Disease Rating Scale. Scores obtained in the activities of daily living and motor examination sections were analyzed to characterize the participants’ functional and motor profile.;To assess the tremor frequency of the most affected upper limb, without compression and with compression. The outcome was measured using an MPU-6050 inertial sensor positioned on the dorsal region of the hand. Tremor frequency values were analyzed under the conditions without and with the compressive band, observing possible changes in frequency during the compression condition compared with the no-compression condition.;To assess fine motor function of the most affected upper limb. The outcome was measured using the Nine-Hole Peg Test. Test completion time was analyzed under the conditions without and with the compressive band, observing a possible improvement in fine motor performance in the compression condition.;To assess gross motor function of the most affected upper limb. The outcome was measured using the Box and Block Test. The number of blocks transferred within 1 minute was analyzed under the conditions without and with the compressive band, observing a possible improvement in gross motor performance in the compression condition.;To assess sensory accommodation to the compressive stimulus in the most affected upper limb over 30 minutes. The outcome was measured by comparing the records obtained immediately after placement of the compressive band, after 15 minutes of use, and after 30 minutes of use. Tremor amplitude and applied pressure values were analyzed over time, observing possible changes in the response to the compressive stimulus during the assessment period.;To assess the amount of pressure applied to the most affected upper limb during the use of the compressive band. The outcome was measured using FSR402 resistive memb | — |
Countries
BR
Contacts
Public ContactNoemi Araújo
Faculdade de ciências médicas - Universidade de Pernambuco
Outcome results
None listed