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Inspiratory muscle training and Inflammatory bowel disease

Effects of inspiratory muscle training on cardiovascular autonomic control and systemic inflammation in patients with Inflammatory bowel disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4bk3yjb
Enrollment
Unknown
Registered
2025-04-04
Start date
2025-04-06
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

crohn disease

Interventions

A sample will consist of 30 participants with inflammatory bowel disease, who will be randomly allocated into two groups, carried out by computer program, the experimental group, participants 15, and
the inspired training carried out in the participants' homes, while the tests, in person, at the facilities of the Experimental and Applied Exercise Physiology Laboratory, located at the Biomedical In
E02.190.525.186

Sponsors

Instituto Biomédico
Lead Sponsor
Instituto Biomédico
Collaborator

Eligibility

Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Men and women; minimum age of 18 and a maximum of 60 years; participants with inflammatory gastrointestinal diseases in remission for 3 months; participants with the ability to walk independently; participants with no change in medication for at least 30 days prior to the start of the testing protocol; complete blood count, liver enzymes and inflammatory markers performed no more than 30 days ago

Exclusion criteria

Exclusion criteria: History of chronic or acute cardiorespiratory disease, except controlled arterial hypertension; acute pathologies that affect blood pressure and breathing; body mass index 35 kg/m2; cardiac arrhythmia that prevents measurement of cardiac autonomic control; anemia; smoking; previously diagnosed respiratory disorders and lung capacity below 80% of the value predicted by spirometry; severe postural deviation in the sternum or spine such as scoliosis, hyperkyphosis or hyperlordosis that influence the respiratory pattern; osteomyoarticular dysfunction that alters gait and requires assistive devices for walking

Design outcomes

Primary

MeasureTime frame
The expected results after training the inspiratory muscles are better cardiovascular autonomic control and a reduction in inflammatory markers.

Secondary

MeasureTime frame
An improvement in endothelial function, an increase in functional capacity, and an improvement in the quality of life of post-training participants are expected.

Countries

Brazil

Contacts

Public ContactGabriel Rodrigues

Universidade Federal Fluminense

gabrieldias@id.uff.br+55 21 2629-2561

Outcome results

None listed

Source: REBEC (via WHO ICTRP)