Melasma
Conditions
Interventions
Intervention group: 6 women with facial melasma. In addition to tinted sunscreen, all participants will be submitted to an application of subcutaneous polydioxanone threads in the zygomatic region aff
Sponsors
Faculdade de Medicina de Botucatu (FMB - Unesp)
Faculdade de Medicina de Botucatu (FMB - Unesp)
Eligibility
Sex/Gender
Female
Age
45 Years to 60 Years
Inclusion criteria
Inclusion criteria: Women over 45 years old, with facial melasma affecting the zygomatic region bilaterally and another area of the face (control) and phototypes II to V (Fitzpatrick). Participants must avoid sun exposure during the study period.
Exclusion criteria
Exclusion criteria: Pregnant and lactating women; individuals who are using other clarifying substances and those who refuse to be photographed; women who work with photo exposure; carriers of autoimmune diseases; menopausal women;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcomes will be the reduction of the mMASI score. Participants will be assessed for primary outcomes at the time points: T0, T60, T120 and T180.;The primary outcome will be the reduction of the colorimetric index in the treated and control areas. Participants will be assessed for primary outcomes at the time points: T0, T60, T120 and T180. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes will be evaluated through MELASQoL, dermatoscopy and clinical evaluation by the participant and the researcher, both at T0 and T60 and T90. | — |
Countries
Brazil
Contacts
Public ContactHelio Miot
Outcome results
None listed