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Comparison of methods of oral rehydration therapy in children with acute diarrhea.

Comparison of methods of oral rehydration therapy in children with acute diarrhea.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4b45px
Enrollment
Unknown
Registered
2012-04-10
Start date
2011-03-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Children hospitalized with acute diarrhea and dehydration

Interventions

Group A (standard):Thirty-four children received during the maintenance phase of the standard Oral Rehydration Solution (ORS) with 90mmol/L sodium, 111mmol/L glucose and osmolarity of 311mmol/L, in eq
other

Sponsors

Centro de Pesquisa Fima Lifshitz
Lead Sponsor
Universidade Federal da Bahia
Collaborator

Eligibility

Sex/Gender
Male
Age
2 Months to 30 Months

Inclusion criteria

Inclusion criteria: Male children 2-30 months old Pre-classified with acute diarrhea and dehydration.

Exclusion criteria

Exclusion criteria: Only breastfeeding nutrition With severe malnutrition With clinical suspicious or documented signs and symptoms of chronic illness or systemic infection Not able to understand the nature of study and sign the inform consent

Design outcomes

Primary

MeasureTime frame
Reduction of the duration of diarrhea (hours), as well as stool output (ml / kg / h) due to a lower water intake (ml / kg / day) without an increase in dehydration. Water Balance held every 8hours: All losses (faeces, vomit and urine output) collected in containers and clothing pre-weighed were measured on precision scales (OHAUS Triple Beam Balance Model, 2610 g capacity 5lb 2oz). All oral intake was measured using the technique of rest-intake using a precision scale (DIGIPESO, model DP-3000, 3 kg capacity and accuracy 0.5 g).

Secondary

MeasureTime frame
No impairment in weight gain or caloric intake, No increase in the number of vomiting, nor disorder hydroelectrolytical. The weight of each naked child was obtained in the same time (06, 14 and 22h) and before the meals using digital scale balance model BP Fillizola Baby™ with accuracy of 5grams. For the measurement of caloric intake and vomiting, was performed the same procedure performed for the primary outcomes. Electrolyte abnormalities (hypernatremia (Na> 150mmol / l), hyponatremia (Na <130 mmol / l) and hypokalemia (K <3 mmol / l)) were evaluated by laboratory tests.

Countries

Brazil

Contacts

Public ContactPatricia;Hugo Mendes;Ribeiro Jr

Centro de Pesquisa Fima Lifshtz/UFBA;Centro de Pesquisa Fima Lifshtz/UFBA

pat-almeida@ig.com.br;hugocrj@ufba.br(55 71) 3283-8346;(55 71) 3283-8100

Outcome results

None listed

Source: REBEC (via WHO ICTRP)