Cicatrix, keloid, regeneration, wound healing
Conditions
Interventions
Experimental group: 27 patients selected for the inclusion criteria who underwent abdominal cosmetic surgery (abdominoplasty), whose scar on the right side was treated with topical therapy with Led (h
Procedure/surgery
Other
Sponsors
Pontifícia Universidade Católica do Rio Grande do Sul
INSERM U1051 Institut des Neurosciences de Montpellier
Eligibility
Age
18 Years to 49 Years
Inclusion criteria
Inclusion criteria: Patients with informed consent signed; caucasian; patients underwent abdominoplasty; patients in whose immediate postoperative period does not show signs of distress or mechanical trauma of the sutured tissue; BMI between 20-30 kg/m2
Exclusion criteria
Exclusion criteria: Patient with indication of multifunctional abdominoplasty or previously undergone to bariatric surgery; patients previously undergoing abdominal surgery that could compromise the vitality of the abdominal flap (cholecystectomy laparotomy for weapon or firearm trauma); patients with autoimmune disorders of collagen metabolism; smoking; diabetes mellitus; chronic hypertension; alcoholism; bleeding disorder; protein malnutrition; immunodeficiency; patients suffering acute or chronic dermatitis or using pharmacological treatment with corticosteroids or chemotherapy; patients undergoing radiation therapy for any reason in the abdominal-pelvic region; patients with known healing disorders (hypertrophic scars or keloids); patients with intestinal bad absorption; patients who have been conducting strict diet prior to surgery; patients who are using another type of product or drug for preventing or improving healing; patient presenting tattoo in the abdominal region and difficult the postoperative evaluation of the scar; patients with medical conditions that interfere with normal wound healing (vitamin C deficiency; iron deficiency; anemia)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improved of cicatrization evaluated by Vancouver and Draajiers assessment scales the first, sixth and twelfth months postoperative observing the decrease of the score scales considering a variation of more than 5% of the observations pre and post intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Improved of cicatrization evaluated with preoperative biopsies, one, six and twelve months postoperative biopsies observing the collagen quantity and fibroblast migration considering a variation of more than 5% of the observations pre and post intervention;Improved of cicatrization evaluated by profilometry technique the first, sixth and twelfth months postoperative observing the decrease of the surface irregularities considering a variation of more than 5% of the observations pre and post intervention | — |
Countries
Brazil
Contacts
Public Contactrenato franz ramos
Pontifícia Universidade Católica do Rio Grande do Sul
Outcome results
None listed